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HHMI Bulletin Fall 2012 Robert Tjian |
President's Letter: Stabilizing Forces Recognizing the role of research professionals in today's laboratory organizations is important not only to the individuals who contribute their services but also to the research enterprise as a whole. |
HHMI Bulletin Nov 2011 Jim Keeley |
Getting Back to the Bench All Janelia Farm group leaders, fellows, and junior fellows actively engage in research. They work to discover the basic rules and mechanisms of the brain's information-processing systems and developing biological and computational techniques for creating and interpreting biological images. |
HHMI Bulletin Feb 2011 |
President's Letter Postdoctoral scientists have played an essential role in advancing discovery research in the life sciences for more than a century. |
HHMI Bulletin May 2011 Amber Dance |
The Best of Times and the Worst of Times for Postdocs Fresh from a Ph.D. in virology, Nancy Van Prooyen is carving her own scientific niche. She's taking on the little-known fungal pathogen, Histoplasma capsulatum, as a postdoctoral fellow at the University of California, San Francisco. |
HHMI Bulletin Nov 2011 Mitch Leslie |
Creating Internal Maps Combining complementary skills, a team of neuroscientists studies how flies navigate their surroundings. |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. |
HHMI Bulletin February 2011 Kendall Powell |
The Next Generation The postdoctoral fellowship for biologists is a high-pressure series of challenges to join the best lab after graduate school, execute and publish stellar science, and then secure a full-time position afterward. |
HHMI Bulletin Spring 2013 Erin Peterson |
I Am a Scientist Science benefits from diversity, says David Asai, senior director of HHMI's precollege and undergraduate science education programs. "Finding solutions to hard scientific problems often depends on the diversity of the problem solvers." |
HHMI Bulletin May 2012 Erin Peterson |
Making Bigger Better University of Texas at Austin Freshman Research Initiative student Holli Duhon describes her research. |
HHMI Bulletin Fall 2012 Ivan Amato |
The View from Here "Every major advance in imaging technology precipitates a new round of breakthroughs in cell biology," says structural biologist Grant Jensen, an HHMI investigator at the California Institute of Technology. |
HHMI Bulletin Fall 2012 |
Medical Fellows Get a Chance to Try Research This past summer, 70 medical, dental, and veterinary students put their courses and rotations on hold to focus on laboratory research. |
HHMI Bulletin Winter 2013 John Carey |
Sydney Brenner: Model of Success At the famously innovative Medical Research Council's Laboratory of Molecular Biology in Cambridge, England, Sydney Brenner made his mark. Today, Brenner spends part of his year at Janelia, as a senior resident fellow. |
HHMI Bulletin Nov 2010 |
New live action microscopy lets scientists follow the first days of a zebrafish embryo's development The promise of live embryo imaging is unquestionable. Light-sheet microscopy will allow scientists for the first time to describe in detail the processes of development in complex vertebrates |
Bio-IT World August 13, 2002 Kevin Davies |
Hughes Offers a Helping Hand Under the assured leadership of Nobel Laureate Tom Cech, the Howard Hughes Medical Institute (HHMI) is increasingly applying its considerable resources to foster imaginative, interdisciplinary biomedical research and education. |
HHMI Bulletin Spring 2013 Robert Gutnikoff |
Lab on the Move When the high school classroom setting is lacking, enter the mobile lab from the University of Texas -- Pan American, in Edinburg, funded with HHMI grants in 2004 and 2008. |
HHMI Bulletin Aug 2010 Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
HHMI Bulletin May 2010 Jeffrey M. Perkel |
A Brighter View of the Brain in Action A protein sensor is beefed up to illuminate the language of neural networks. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
HHMI Bulletin Fall 2012 Trisha Gura |
Teaching Genomics, Plainly Students at Franklin & Marshall College, searched databases of gene sequences, engineered bacteria to shuttle mutated genes into cells, and captured images of how those cells reacted to the alterations. |
HHMI Bulletin May 2011 Amy Maxmen |
Shirley Tilghman: The Future of Science Ultimately, we want to create a biomedical enterprise that produces the best science and brings out the best in the people engaged in it. Today the training path has become too long. |
HHMI Bulletin Aug 2011 |
Let's Get Small Tim Harris develops tools neuroscientists can use to measure the brain's activity, to give them a quantitative view inside the elaborate structure of the brain. |
HHMI Bulletin Fall 2012 Elise Lamar |
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. |
BusinessWeek December 12, 2005 Michael Arndt |
Cancer Cells With A Death Wish Is Abbott Labs' Stephen Fesik closing in on a way to make cancer cells self-destruct? |
HHMI Bulletin May 2010 Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells. |
Popular Mechanics November 27, 2007 Alex Hutchinson |
Stem Cells 2.0: Beyond the Hype, Engineers Look to Build Fast Engineers play the important role of making lab bench discoveries reproducible and efficient for use in industry. |
HHMI Bulletin May 2010 |
HHMI Investigator Sean Carroll Named Vice President for Science Education HHMI announced in April that Sean Carroll, an award-winning scientist, author, and educator, will become the Institute's vice president for science education. |
HHMI Bulletin Nov 2011 Katharine Gammon |
Room to Grow -- and Learn For undergraduates who have the opportunity to do high-level research, the experience can be unforgettable. |
HHMI Bulletin February 2011 |
New International Competition for Early Career Scientists The biomedical competition is aimed at helping up to 35 early career scientists establish independent research programs. Scientists trained in the United States who are now running a lab in any eligible country may apply. |
T.H.E. Journal September 2001 Kyle Forinash & Raymond Wisman |
The Viability of Distance Education Science Laboratories The history of science from Galilei on has primarily been the reconciliation of theory with imperfect experimental data. Providing a similarly compelling laboratory experience for a student, especially to one not physically present, is problematic... |
Wired May 2003 Brendan I. Koerner |
The Lab that Fell to Earth Once the center of the technology research universe, the storied MIT Media Lab is now teetering on the brink of breakup -- or, even worse, irrelevance |
HHMI Bulletin Fall 2012 R. John Davenport |
Hanchuan Peng: SmartScopes Even when he launched his career as an engineer and computer scientist, Hanchuan Peng was drawn to the beauty of biology. He is a leader in developing sophisticated ways to make sense of biological images. |
HHMI Bulletin Aug 2010 Virginia Hughes |
Glimpsing Inside a Moving Fruit Fly's Brain Vivek Jayaraman wants to capture, in real time, how the fly's brain responds to a changing environment. Ultimately, he hopes to uncover very basic patterns -- "algorithms" -- of fly brain activity that hold true in more complex brains including, presumably, ours. |
IEEE Spectrum February 2011 Tekla S. Perry |
Dream Jobs 2011: Insect Imagineer Gus Lott designs virtual reality systems for bugs and rats so that we can study their brains -- and ours |
HHMI Bulletin Winter 2013 Robert Tjian |
President's Letter: Taking the Long View This October, I was honored to be present at the official opening of the KwaZulu-Natal Research Institute for Tuberculosis and HIV, or K-RITH, in Durban, South Africa. This initiative brings a new dimension to HHMI's commitment to international research. |
Bio-IT World October 2006 Kevin Davies |
Marshall's IT Plan for Janelia Farm One would expect the new VP of IT to call Janelia Farm the most exciting project he has ever participated in. But coming from the man who oversaw the impressive IT infrastructure to assemble the human genome at Celera Genomics six years ago, that is particularly noteworthy. |
HHMI Bulletin May 2012 |
President's Letter: Critical Thinking Though our efforts to improve the training of STEM teachers and students are modest in the big picture, we hope the work becomes an amplifying mechanism. And with new initiatives coming out of our science education group, we plan to have an even bigger influence on STEM education in this country. |
Wired July 2006 Annalee Newitz |
Code of the Caveman A new DNA mapping technique may solve an ancient mystery: Do modern humans carry Neanderthal genes? |
HBS Working Knowledge December 5, 2011 Carmen Nobel |
It's Alive!: Business Scholars Turn to Experimental Research Researchers use field and lab experiments to better understand the logic of real-world decisions, which sometimes fly in the face of established economic theory. |
HHMI Bulletin Winter 2013 Lauren Ware |
Musical Magnet Andrey Shaw sees many parallels between playing music and conducting scientific research. "Much of what you do is tedious and repetitive. It requires a Zen-like state -- you have to sit down, focus, and be in the moment," he says |
Chemistry World May 30, 2014 |
Taking responsibility Sara Cooper talks to Neil Withers about safety in the lab and how it's up to everyone, from boardrooms to students, to create a safe environment |
Chemistry World February 2009 Derek Lowe |
Column: In the pipeline How important is it to have the best equipped lab? One group holds that there's little effect at all, that good scientists can do good work with whatever's at hand. |
HHMI Bulletin May 2012 Nicole Kresge |
Better Than a Straitjacket Scientist Sandhya P. Koushika devised an inexpensive, simple way to get the worms to pause so she can image cellular activity in the transparent creatures. |
HBS Working Knowledge January 5, 2011 |
Funding Unpredictability Around Stem-Cell Research Inflicts Heavy Cost on Scientific Progress Society pays a high price for randomization of research support -- a fact that, sadly, is not recognized by the public, the media, or politicians. |
Bio-IT World April 16, 2004 Fowler & Cardin |
Cinching Synergy with a Contract Lab The keys to developing a synergistic relationship are identifying the right partner, clearly defining expectations, and communicating regularly and honestly. Follow these steps to success for lab services outsourcing. |
Chemistry World February 21, 2013 Akshat Rathi |
NO for longevity US researchers may have direct evidence for nitric oxide's apparent special powers, at least in the nematode model organism Caenorhabditis elegans. |
HHMI Bulletin February 2011 Kathryn Brown |
Curved Wings A scientist-sculptor says "My philosophy is that there are only two things you can do to keep creative, like a child: art and science." |