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HHMI Bulletin
May 2012
Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons.   |
Chemistry World
June 2, 2006
Jon Evans |
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. |
HHMI Bulletin
Nov 2011
Deborah Franklin |
Helping Preemies Treating myelin injuries and tracking brain cell development to rescue the littlest patients. |
HHMI Bulletin
Aug 2010
Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
Scientific American
July 3, 2006
Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
HHMI Bulletin
Winter 2013
Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World
September 15, 2011
Sarah Farley |
Making Nerve Pathways in Chips for Brain Studies Scientists have now developed a way to reconstruct neuronal networks in a micro-fluidic system to more closely mimic the directional neuronal pathways found in the brain. |
BusinessWeek
June 13, 2005
John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
Chemistry World
October 26, 2011
Kate McAlpine |
Dismissing gatekeepers for enhanced nerve control US researchers have invented a better way to stimulate or block nerve impulses by coating an electrode with a membrane that can control the local concentration of ions. |
HHMI Bulletin
Aug 2011 |
Seeing is Believing Today, researchers are finding clever ways to deliver long-lasting, healthy genes without triggering a serious immune response. |
The Motley Fool
July 30, 2007
Brian Orelli |
Another Blow to Gene Therapy The FDA shuts down a clinical trial, tripping up Targeted Genetics and possibly its competitors. A subject in the trial of their gene therapy arthritis medication died shortly after taking the drug. |
BusinessWeek
April 22, 2010
Rob Waters |
Gene Therapy Takes a Turn for the Better Researchers and investors are heartened by advances in gene therapy. Analysts say revenues are still several years off, however. |
Salon.com
June 1, 2000
Tabitha M. Powledge |
Gene therapy R.I.P.? When the country's biggest gene therapy institute was ordered to stop testing on humans last week, the action marked the end of an era fraught with dubious claims to success and a mess of unreported adverse effects. |
HHMI Bulletin
Aug 2010
Janelle Weaver |
Scientists Identify a Gene That Drives Fruit Fly's Thirst Kristin Scott, an HHMI early career scientist at the University of California, Berkeley, has uncovered a gene, called pickpocket 28 (ppk28), that regulates fruit flies' ability to detect water and how much time they spend drinking. |
HHMI Bulletin
Spring 2013
Amy Maxmen |
Ring Around the Axon Xiaowei Zhuang and her team used a microscopy technique called STORM to show that actin protein forms evenly-spaced rings around the axons of nerve cells. |
HHMI Bulletin
May 2011
Sarah C.P. Williams |
The Pace of Evolution A close look at the human genome shows the slow and steady beat of adaptation. |
Chemistry World
February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |
Salon.com
December 19, 2000
Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
HHMI Bulletin
Nov 2010
Amber Dance |
A 3-D Computer Model Exposes the Brain's Neuropil, Where Learning And Memory Begin Learning and memory depend on nerve cells and support cells called astrocytes. Nerves have "output" channels -- long slender axons that reach out to other nerves -- and "input" channels -- branching dendrites that collect incoming signals. |
