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Chemistry World November 27, 2013 Derek Lowe	Rolling boulders uphill A lot of preclinical projects don't even get off the ground, and many that do still never deliver anything to the development groups.
Chemistry World December 17, 2012 Patrick Walter	RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists.
Chemistry World October 5, 2006 Mark Peplow	Boron Shows Its Negative Side A molecule that hosts a negatively-charged boron atom could prove to be an exciting addition to the chemist's toolbox, according to researchers who have isolated the anion as its lithium salt.
Chemistry World June 2008 Sarah Houlton	Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success
Chemistry World June 2011	Column: In the pipeline Chemists are human. Humans are hierarchical. Therefore...well, therefore, you'll find a number of different roles and levels for scientists in a drug company's labs. Here's a rough ordering, from least experienced to most.
Chemistry World February 21, 2007 Tom Westgate	Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules.
Chemistry World January 2011	Column: In the pipeline Some medicinal chemists can't get enough fluorines in their molecules. The love-hate relationship is explained.
Chemistry World June 14, 2012 David Bradley	Tripling up on boron bonds Carbon and nitrogen are well known for their triple bonds, but making stable compounds with a triple bond between two boron atoms hadn't been achieved despite the computational possibilities. Until now.
Chemistry World August 2008	Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?
Chemistry World December 13, 2009 Lewis Brindley	Breaking the strongest bonds Chemists have uncovered a way to sever two of the strongest bonds in chemistry - in dinitrogen and carbon monoxide - and make useful organic compounds.
Chemistry World December 1, 2014 Derek Lowe	Progress at the pace of the slowest Chemistry is a means to an end in drug research, not an end in itself, and that can take some getting used to. It's worth thinking about where chemistry fits into the big picture.
Chemistry World December 20, 2010 Hayley Birch	Atomic weights change to reflect natural variations The atomic weights for ten elements are to be expressed as intervals rather than single values, the International Union of Pure and Applied Chemistry has announced.
Chemistry World March 25, 2012 Phillip Broadwith	Germanium-Oxygen Double Bond Takes Centre Stage The first compound with a germanium-oxygen double bond has been created by Japanese scientists.
Chemistry World August 2009 Derek Lowe	Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
Chemistry World April 30, 2015 Rebecca Trager	Anton Toutov: The power of potassium Toutov says the potassium catalyst he has developed costs only about $30 per mole, or less. 'It is safer and non-toxic, and a lot more cost-effective,' he states.
Chemistry World June 1, 2012 Derek Lowe	Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that.
Chemistry World June 2010	Column: In the pipeline Derek Lowe looks into his crystal ball to see what the future of medicinal chemistry might be
Chemistry World December 2008	Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project.
Chemistry World April 14, 2009 Lewis Brindley	Osmium and pyridine ring together Organic chemists in China have found a way to put osmium into a pyridine ring - leading to the synthesis of the first metallapyridinium complex.
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World August 2007 Derek Lowe	Opinion: In the Pipeline Process chemists just don't get the credit they deserve.
Chemistry World October 5, 2011 Simon Hadlington	Turning Carbon Dioxide Into Chemicals with an Amine Chemists in France have devised a new way to turn carbon dioxide into a useful chemical building block.
Chemistry World July 2008 Kevin Rogers	What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril
Chemistry World October 2009	Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions
Chemistry World November 2006 Yfke Hager	Careers: Heartfelt Chemistry After working in New Zealand, medicinal chemistry tempted Ashley Jarvis back to the UK. He now works in his dream field.
Chemistry World July 9, 2012 Phillip Broadwith	'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom.
Chemistry World June 25, 2012	Chemistry in Evolution In "Evolution's Destiny," the authors explore the role of chemistry in evolution, and in particular the changing role of inorganic elements in the evolution of the ecosystem.
Chemistry World August 17, 2009 James Urquhart	New method for fluorinating compounds Fluorine atoms are incorporated into aromatic organic compounds for many reasons, including their ability to increase metabolic stability, solubility and bioavailability.
Chemistry World August 21, 2008 Fred Campbell	Double bonding with silicon In a landmark for silicon chemistry, US researchers have reported the first stable silicon (0) compound to contain a silicon-silicon double bond.
Chemistry World March 2006	Letters Chemistry's changing face... Exeter's chemistry closure... DDT ditty... Chlorine in poetry... etc.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World March 5, 2007 Richard Van Noorden	Desperately Seeking Silicon Silicon has been blamed for the faulty fuel that caused thousands of UK cars to break down last week. How can a silvery-gray semi-metal popularly known to be used in computer chips have found its way into gasoline?
Chemistry World November 30, 2012 Andy Extance	Chemists cull compounds using 'intuition' Medicinal chemists might be using far fewer parameters to choose candidate fragments for a screening collection than they think they do. Their choices can be mimicked based on just one or two properties, a team led by researchers at Swiss-headquarted pharmaceutical firm Novartis has found.
Chemistry World April 2009 Derek Lowe	Column: In the pipeline The author considers the problems of addressing drug development out of sequence
Chemistry World November 22, 2013 Lars Ohrstrom	30-second elements Periodic table aficionados and hardcore inorganic chemists will find amazing new facts, while the layman is offered captivating, albeit rhapsodic, insights into the world of chemistry and its applications in this book edited by Eric Scerri.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World January 5, 2016 Philip Ball	The periodic table name game The International Union of Pure and Applied Chemistry works to standardize the names of new elements around the world. Now, following its confirmation of the discovery of four new elements it's time to choose new names that will forever remain a part of the periodic table.
Chemistry World April 2011	Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good.
Reactive Reports Issue 45	Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question...
ONLINE Sep/Oct 2007 Svetla Baykoucheva	A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information.
Chemistry World June 3, 2013 Andrea Sella	Moissan's furnace Henri Moissan was a French inorganic chemist (1852 -- 1907). He discovered fluorine, pioneered fluorine chemistry and high-temperature synthesis
Chemistry World December 10, 2008 Simon Hadlington	Alcohol enantiomer conundrum cracked UK chemists have discovered a straightforward new way to make chiral tertiary alcohols that gives selective access to either enantiomer.
Chemistry World October 29, 2009 Phillip Broadwith	Two metals are better than one UK chemists have developed reagents that can metallate ethers and ethene at room temperature without them disintegrating.
Job Journal July 16, 2006 Julia Hollister	Biotech Boom The biotech field offers promising jobs in a profession that's expanding faster than you can spell biotherapeutics.
Chemistry World October 30, 2009 Ned Stafford	Celebrating chemistry There's a big birthday celebration happening in Marburg, Germany, today, attended by about 800 chemists, to commemorate the birth of chemistry as an academic subject.
Chemistry World August 15, 2011 Simon Hadlington	Trifluoromethylation Made Easy US researchers have discovered a simple, low-cost way to add fluorine atoms to heteroaromatic rings.
Chemistry World May 13, 2015 Stephen McCarthy	Venoms to drugs: venom as a source for the development of human therapeutics The book is well-constructed, starting with an overview of the evolutionary origins of venoms and how these relate to common structures, followed by a guide to modern bioinformatics methods and their application to research in this field.
Chemistry World May 8, 2014 John Emsley	The elements: an illustrated history of the periodic table Tom Jackson is a prolific writer of popular science books aimed mainly at children. He's written more than 80 of them, and now he's turned his lively mind to making the history of the periodic table both informative and interesting.
HHMI Bulletin Nov 2011 Sarah C. P. Williams	Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems.
Chemistry World December 18, 2012 Caryl Richards	Boron vapor trail leads to heterofullerenes A team of scientists has developed a simple way to synthesize heterofullerenes -- fullerenes with atoms other than carbon in their structure -- by exposing fullerene to boron vapor during their growth.