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Chemistry World September 1, 2011 Josh Howgego	Small molecules open gates to the brain New tools have been developed which make it possible to chemically shut down nerve cells in the brain at will and study the effects on behavior. The tools - modified ion channels - mean the causal relationship between individual nerves and behavior can be directly studied.
HHMI Bulletin May 2011 Sarah C.P. Williams	The Very Hungry Mouse Activating one set of neurons makes a mouse eat, and eat, and eat.
HHMI Bulletin May 2010 Jennifer Michalowski	Enter the Samurai Unlike many scientists, Loren Looger doesn't frame his work around a central question. Instead, he has constructed a research program that branches into a broad range of biological investigations.
HHMI Bulletin Aug 2011	Let's Get Small Tim Harris develops tools neuroscientists can use to measure the brain's activity, to give them a quantitative view inside the elaborate structure of the brain.
HHMI Bulletin May 2010 Jeffrey M. Perkel	A Brighter View of the Brain in Action A protein sensor is beefed up to illuminate the language of neural networks.
HHMI Bulletin May 2011 R. John Davenport	Wired for Smell Circuits of excitation and inhibition help the brain interpret odors.
HHMI Bulletin May 2012 Sarah C.P. Williams	Hungry for Pleasure, Hungry for Food Our drive to eat can be based on physical hunger or desire. The two aren't as separate as once thought.
HHMI Bulletin Nov 2011 Jim Keeley	Getting Back to the Bench All Janelia Farm group leaders, fellows, and junior fellows actively engage in research. They work to discover the basic rules and mechanisms of the brain's information-processing systems and developing biological and computational techniques for creating and interpreting biological images.
HHMI Bulletin May 2010 Ivan Arnato	Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells.
HHMI Bulletin February 2012 Marc Wortman	Where Does It Hurt? Researchers are getting to the molecular details of pain's circuitry to answer the question with real specificity.
Chemistry World March 9, 2011 Simon Hadlington	Chemical mystery of antifungal compound solved US researchers have applied synthetic organic chemistry to crack a mystery that has baffled scientists for more than 50 years: how the powerful, naturally occurring antifungal compound amphotericin B interacts with sterols in cell membranes.
Chemistry World June 13, 2007 Richard Van Noorden	Why Cold is Such a Pain We'd all like to avoid the sting of winter air and the agony of moving frozen fingers. Scientists have discovered why extreme cold hurts, and created hardy mice who can freeze painlessly to blocks of ice.
Chemistry World August 1, 2012 Laura Howes	See, blind mice A new compound, developed by scientists at California University, Berkley, US, has allowed blind mice to see temporarily.
HHMI Bulletin May 2011 Corinna Wu	Mouse Cam Tracking techniques offer a long-term view into the mouse brain.
HHMI Bulletin Aug 2010 Janelle Weaver	Scientists Identify a Gene That Drives Fruit Fly's Thirst Kristin Scott, an HHMI early career scientist at the University of California, Berkeley, has uncovered a gene, called pickpocket 28 (ppk28), that regulates fruit flies' ability to detect water and how much time they spend drinking.
HHMI Bulletin Winter 2013 John Carey	Sydney Brenner: Model of Success At the famously innovative Medical Research Council's Laboratory of Molecular Biology in Cambridge, England, Sydney Brenner made his mark. Today, Brenner spends part of his year at Janelia, as a senior resident fellow.
HHMI Bulletin Winter 2013 Rabiya Tuma	Sister Act As a systems neuroscientist, Yang Dan integrates functional studies in animals with computer programs, computational tools, and statistics.
Technology Research News January 29, 2003 Kimberly Patch	Tiny hole guides atoms against tide Researchers in Poland have made a synthetic device that uses an electrical field and an extremely small, conical pore in a thin film of material to coax potassium ions through the artificial membrane against their electrochemical potential.
Chemistry World April 30, 2009 Nina Notman	Long live lipid membranes Scientists in the US have massively extended the lifetime of lipid membranes, with potential implications for the pharmaceutical industry
Chemistry World February 24, 2011 Carl Saxton	Mapping brain networks US scientists have created a model of the ring-shaped networks of neurons in the brain, which could help researchers to understand small changes within diseased brain cells.
Chemistry World November 15, 2012 David Bradley	DNA folds up into a synthetic ion channel An artificial ion channel that spans a synthetic lipid membrane has been created using DNA origami by researchers in Germany and the US.
Chemistry World October 3, 2007 Lewis Brindley	Spicing up Pain Relief Scientists in the US have developed an anaesthetic that can completely block pain without causing numbness. The technique uses capsaicin - the active ingredient in chilli peppers - to target only pain-sensing neurons, and not those associated with feeling or movement.
Chemistry World April 5, 2007 Victoria Gill	Target for Memory-Enhancing Pills Identified Researchers have taken a step towards developing a pill that could improve memory by pinpointing and testing a potential target enzyme in the brain.
HHMI Bulletin Aug 2010 Virginia Hughes	Glimpsing Inside a Moving Fruit Fly's Brain Vivek Jayaraman wants to capture, in real time, how the fly's brain responds to a changing environment. Ultimately, he hopes to uncover very basic patterns -- "algorithms" -- of fly brain activity that hold true in more complex brains including, presumably, ours.
Chemistry World March 2, 2009 James Urquhart	Shining a light on neural activity US researchers have developed a new way to activate brain neurons that could lead to less invasive methods of restoring function in damaged nerves and brain tissue.
Chemistry World September 7, 2008 Simon Hadlington	Coupled proteins to reveal drug hits Researchers in France have successfully attached an 'electrical switch' to a key class of membrane proteins targeted by many drugs.
HHMI Bulletin Aug 2011	Karl Deisseroth: In Support of Undirected Research A disease focus can color the scientific process.
IEEE Spectrum May 2009 Prachi Patel	Laser Probes for Brain Experiments Laser-activated probes stimulate brain cells better, say scientists
HHMI Bulletin Nov 2010	DIADEM Contest Moves Neuromapping in the Right Direction In September, DIADEM -- short for Digital Reconstruction of Axonal and Dendritic Morphology -- came to a close, with a tournament-style conclusion between five final teams taking place at HHMI's Janelia Farm Research Campus.
Chemistry World July 2, 2007 Michael Gross	Transistor tuned to ion channel As living cells can detect many compounds with high sensitivity via receptors on their membranes, researchers are keen to exploit them in electronic biosensors. Researchers in Germany now report the feasibility of just such a receptor-cell-transistor biosensor.
Chemistry World March 4, 2010 Andy Extance	Silver sputtered nano chips mimic brain synapse US researchers aiming to emulate the functionality of a cat's brain have developed an easily-fabricated, robust nanoscale device that imitates the connectivity between neurons in the brain.
HHMI Bulletin Spring 2013 Nicole Kresge	Itching to Be Discovered When the receptor for capsaicin -- the chemical that gives heat to chili peppers -- is added to itch-sensing neurons, exposure to the normally painful capsaicin causes itchiness.
HHMI Bulletin Fall 2012 R. John Davenport	Hanchuan Peng: SmartScopes Even when he launched his career as an engineer and computer scientist, Hanchuan Peng was drawn to the beauty of biology. He is a leader in developing sophisticated ways to make sense of biological images.
HHMI Bulletin Spring 2013 Nicole Kresge	Use It or Lose It HHMI investigator Catherine Dulac of Harvard University has uncovered a small molecule that plays a big role in the process of tuning olfactory neurons to the environment.
Wired August 2001 Jennifer Kahn	Let's Make Your Head Interactive The Human Brain Project is combining wet anatomy with next-gen scanning, imaging, and networking to give neuroscience a revolutionary new tool -- the globally accessible online mind...
HHMI Bulletin Aug 2011 Jennifer Michalowski	Memory Cells at the Ready Special neurons give rodents a leg up when facing unfamiliar territory.
HHMI Bulletin May 2010 Randy Barrett	The Silicon Marvel Computational biologists have a need for speed. The computing cluster on the Janelia Farm Research Campus delivers the performance they require at a mind boggling 36 trillion operations per second.
IEEE Spectrum December 2010 Versace & Chandler	MoNETA: A Mind Made from Memristors DARPA's new memristor-based approach to Artificial Intelligence consists of a chip that mimics how neurons process information
IEEE Spectrum August 2012 Steve Furber	Low-Power Chips to Model a Billion Neurons A miniature, massively parallel computer, powered by a million ARM processors, could produce the best brain simulations yet
National Defense October 2009 Jean & Erwin	On The Road to More Fuel-Efficient Vehicles A123Systems, a lithium ion battery producer, has teamed with the Energy Department's Oak Ridge National Laboratory to develop fuel-efficient vehicle technology. Funding for the joint project is being provided under the Recovery Act.
Scientific American October 2, 2005 Diane Martindale	One Face, One Neuron A recent study indicates that our brains employ far fewer cells to interpret a given image than previously believed, and the findings could help neuroscientists determine how memories are formed and stored.
BusinessWeek September 11, 2006 Catherine Yang	Going Big By Going Digital By adding extra channels, ION Media hopes to make the most of the transition from analog TV.
Technology Research News January 14, 2004	Melted fibers make nano channels Researchers from Cornell University have devised a simple, inexpensive way to construct fluidic channels whose corners are elliptical rather than sharp, which permits fluid to flow more freely.
Chemistry World October 6, 2015 Tim Wogan	Rolled-up electrodes record brain activity without scarring Ultra-flexible neural electrodes have been created that can more precisely measure brain activity without causing tissue scarring.
Chemistry World September 15, 2011 Sarah Farley	Making Nerve Pathways in Chips for Brain Studies Scientists have now developed a way to reconstruct neuronal networks in a micro-fluidic system to more closely mimic the directional neuronal pathways found in the brain.
HHMI Bulletin February 2011 Kathryn Brown	Curved Wings A scientist-sculptor says "My philosophy is that there are only two things you can do to keep creative, like a child: art and science."