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Chemistry World
April 17, 2013
Mark Peplow |
Sanofi launches malaria drug production On 11 April, the Paris-based pharmaceutical company Sanofi officially launched a new production facility in Garessio, Italy, to make artemisinin -- the precursor to artemisinin-based combination therapies, the most effective drugs against the deadliest malaria parasite.   |
Chemistry World
September 10, 2014
Elisabeth Ratcliffe |
Antimalarial flow synthesis closer to commercialization Scientists in Germany have demonstrated the large scale and inexpensive production of a range of antimalarial drugs, using a continuous flow system. |
Chemistry World
May 20, 2015
Andy Extance |
Malaria drug could cash in on green chemistry Green chemistry principles could make synthesizing the frontline antimalarial drug artemisinin both cleaner and cheaper, an industry -- academia collaboration suggests. |
Chemistry World
April 10, 2013
Hayley Birch |
Yeast to make malaria drug on demand A natural biochemical pathway that produces the antimalarial drug artemisinin in the sweet wormwood plant has been fully reconstructed in yeast. |
Chemistry World
December 20, 2012
Laura Howes |
Cutting edge chemistry in 2012 This year saw more work probing the nature of bonding. In Germany, Holger Braunschweig found that reacting a bis(N-heterocyclic carbene)-stabilized tetrabromodiborane with sodium naphthalene gave diborene or diboryne compounds with the world's first stable boron -- boron triple bond. |
Chemistry World
September 19, 2008
Lewis Brindley |
Chemical conversion made twice as green A combination of two green processes - supercritical fluids and photochemistry - could have a bright future for performing environmentally friendly reactions on an industrial scale |
Chemistry World
March 23, 2009
Nina Notman |
First auto carbohydrate synthesiser German researchers have unveiled the first fully automated carbohydrate synthesizer, which they hope will advance development of carbohydrate-based vaccines for the developing world. |
Chemistry World
August 30, 2009
Phillip Broadwith |
C-H oxidation proves its worth US researchers are going against the grain of total synthesis and developing new approaches to complex molecules. |
Chemistry World
October 31, 2012
Paul Docherty |
Epicoccin G The class of natural products known as 2,5-diketopiperazines is both broad and synthetically well-trodden. An important sub-class of these targets are found with a sprinkling of sulfur atoms, and seem particularly well-suited to pathogen-bashing. |
Chemistry World
June 27, 2013
Rachel Cooper |
Self-contained chemical synthesis Scientists in the UK have used reactors made on a 3D printer to complete a three stage organic synthesis. |
Chemistry World
August 18, 2011
Helen Bache |
Sugar injection to beat hospital infection A carbohydrate from the surface of the most virulent strain of the bacterium Clostridium difficile has been synthesised by chemists in Germany. The molecule could be used to develop a vaccine against the infection. |
Chemistry World
July 31, 2014 |
The worldwide chemist Martyn Poliakoff's chemistry research and science outreach have secured him hundreds of thousands of followers around the world. Here is a profile of the internet's favorite 'mad professor' |
Chemistry World
December 9, 2011
Jennifer Newton |
Turning Bacteria's Shield Into a Weapon Against it Scientists in Germany have synthesised the core part of a sugar compound produced by the pathogenic bacteria responsible for meningitis - Neisseria meningitides - which could be used in a vaccine for meningococcal diseases, in particular meningitis B. |
Chemistry World
April 25, 2007
Richard Van Noorden |
Malaria Drug Cures Mice with Single Dose U.S. chemists have adapted a Chinese herbal medicine to create a new generation of antimalarial drugs which could solve some of the current crop's failings. |
Chemistry World
August 22, 2014
Tim Wogan |
Yeast turned into morphine and opioid biofactories Genetically modified yeast can synthesize morphine and semisynthetic opioid pharmaceuticals, researchers in the US have shown. |
Chemistry World
May 3, 2012
Akshat Rathi |
Ranbaxy launches new anti-malarial Synriam It is the first recently developed antimalarial that is not based on artemisinin, one of the most effective treatments for malaria, which has begun to suffer from problems with resistance in recent years. |
Fast Company
September 2006
Tonya Garcia |
Miracle Microbes In the labs of Amyris Biotechnologies, molecular manipulation may yield cheap and effective malaria drugs. |
Chemistry World
December 19, 2007
Hepeng Jia |
Boom and Bust for Antimalarial Industry At first there was a global shortage, but now a surplus of artemisinin threatens to put some drug manufacturers out of business. |
Chemistry World
April 2008
Victoria Gill |
Malaria no More? A fresh round of research funding could put an end to the killer disease. |
Chemistry World
October 5, 2015
Matthew Gunther |
Antiparasitic drugs derived from natural products take 2015 medicine Nobel The 2015 Nobel prize in physiology or medicine has been split between three researchers for unearthing two naturally-occurring antimicrobial products that can fight parasitic diseases such as malaria and river blindness. |
Chemistry World
April 2007
Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
