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Chemistry World
October 12, 2007
James Mitchell Crow
Flow Reactors Enter the Rapids Continuous flow chemistry's promise to shake up synthesis gathered momentum this month, with the first Uniqsis Flow Chemistry Symposium. mark for My Articles similar articles
Chemistry World
January 21, 2013
Michael Parkin
Flow synthesis for anticancer drug UK chemists have used a combination of flow chemistry methods with solid-supported scavengers and reagents to synthesize the active pharmaceutical ingredient, imatinib, of the anticancer drug Gleevec. mark for My Articles similar articles
Chemistry World
August 16, 2009
Tom Bond
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. mark for My Articles similar articles
Chemistry World
October 2007
Derek Lowe
In the Pipeline One of the biggest areas of chemical research these days is in catalytic processes. It's one of the places we can really improve our processes, especially when you count the waste stream (as you should) as part of the total energy bill. mark for My Articles similar articles
Chemistry World
October 2009
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions mark for My Articles similar articles
Chemistry World
August 1, 2013
James Urquhart
Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions. mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
June 2010
Paul Docherty
Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups. mark for My Articles similar articles
Chemistry World
October 31, 2012
Paul Docherty
Epicoccin G The class of natural products known as 2,5-diketopiperazines is both broad and synthetically well-trodden. An important sub-class of these targets are found with a sprinkling of sulfur atoms, and seem particularly well-suited to pathogen-bashing. mark for My Articles similar articles
Chemistry World
January 29, 2014
Elisabeth Ratcliffe
Flow system overcomes reagent incompatibility issues Synthesizing cyclic carbonates could become easier and more efficient thanks to a sequential flow system developed by scientists in the US. mark for My Articles similar articles
Chemistry World
November 2010
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. mark for My Articles similar articles
Chemistry World
January 22, 2014
Eleanor Merritt
Designer esters for complex carbohydrates Scientists based in the US have developed a new strategy to simplify the chemical synthesis of complex carbohydrates. mark for My Articles similar articles
Chemistry World
August 10, 2007
Richard Van Noorden
Azadirachtin Sees First Total Synthesis A complex natural product has finally succumbed to its first total synthesis after 22 years of attempts by eminent organic chemists. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
June 11, 2008
James Mitchell Crow
New Hope for Anticancer Agent The mode of action of a rare natural product with promising cytotoxic activity has been revealed by scientists in the US while a UK group have come up with a particularly efficient chemical synthesis. mark for My Articles similar articles
Chemistry World
November 2007
Derek Lowe
Column: In the Pipeline Chemists are finally going with the flow. mark for My Articles similar articles
Chemistry World
April 2007
Derek Lowe
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? mark for My Articles similar articles
Chemistry World
November 2006
Yfke Hager
Careers: Heartfelt Chemistry After working in New Zealand, medicinal chemistry tempted Ashley Jarvis back to the UK. He now works in his dream field. mark for My Articles similar articles
Chemistry World
May 25, 2007
Richard Van Noorden
Keeping it Green Some chemistry enthusiastically labeled as green may be nothing of the kind, warn researchers who worry that mediocre -- if well-meaning -- science is damaging their subject. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C. P. Williams
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. mark for My Articles similar articles
Chemistry World
April 12, 2013
Melissae Fellet
Elusive atmospheric intermediates reveal some secrets Scientists have found further evidence for the existence of an elusive intermediate implicated in chemical reactions that degrade atmospheric pollutants. mark for My Articles similar articles
Chemistry World
September 10, 2014
Andy Extance
'Assembly line' sculpts carbon chains UK chemists have devised a precise process for building carbon chains a link at a time that packs in more side groups than biologically-derived molecules can. mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Chemistry World
June 19, 2013
John Hayward
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. mark for My Articles similar articles
Bio-IT World
October 2006
Robert M. Frederickson
Fast Track to Compounds and Crystals Nexus Biosystems' IRORI systems allows synthesis of tens to tens of thousands of compounds. Nexus' Kan Reactors are miniaturized devices that contain both a functionalized solid phase support and a unique tag identifier for the synthesis of a discrete compound. mark for My Articles similar articles
Chemistry World
July 12, 2006
Jessica Ebert
Light Sensors From a Test Tube Making electronic components from solutions of chemicals has long been touted as being cheaper and cleaner than conventional manufacturing processes, and researchers now say that it can also deliver better devices. mark for My Articles similar articles
Chemistry World
November 2011
Graeme Armstrong
Good Chemistry We must improve the chemistry between industry and society. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Chemistry World
July 2008
Kevin Rogers
What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril mark for My Articles similar articles
Chemistry World
July 14, 2011
Simon Hadlington
Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor. mark for My Articles similar articles
Chemistry World
March 22, 2012
Ross McLaren
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. mark for My Articles similar articles
Chemistry World
October 1, 2013
Eleanor Merritt
New software for creating green solvents Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Kevin Davies
In Praise of Chemical Diversity How to build better small-molecule libraries. mark for My Articles similar articles
Chemistry World
March 19, 2009
Manisha Lalloo
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings mark for My Articles similar articles
Chemistry World
January 27, 2010
Simon Hadlington
Fruity route to control asymmetric syntheses Chemists in the UK have discovered a quick, cheap and easy way to make a key sulfide reagent that can mediate the formation of chirally selective molecules needed for complex organic syntheses. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
December 20, 2007
Richard Van Noorden
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. mark for My Articles similar articles
Chemistry World
November 25, 2014
Hugh Cowley
Benchtop NMR gives feedback in flow The platform performs algorithm driven organic synthesis using real-time feedback from in-line flow NMR spectroscopy mark for My Articles similar articles
Chemistry World
May 2, 2014
Jennifer Newton
Zoe Schnepp: Green collaboration Zoe Schnepp is a lecturer in the School of Chemistry at the University of Birmingham in the UK. Her group develops simple routes to functional materials. In particular, they use biomass to synthesize materials for applications, such as catalysis and water filtration. mark for My Articles similar articles
Chemistry World
September 17, 2007
Uk Pharma Shifts Manufacturing Overseas Drug firm AstraZeneca has today reiterated that it will outsource drug manufacturing. mark for My Articles similar articles
Chemistry World
September 2008
Derek Lowe
Column: In the pipeline The author remembers leaving the ivory towers of academe to trade 'unusual and beautiful' for 'useful' mark for My Articles similar articles
Chemistry World
July 2008
Mark Peplow
Editorial: There's plenty of room in the middle Today, chemists and biologists are looking at the space between their own disciplines and asking big questions about where science at the interface might lead them. mark for My Articles similar articles
Chemistry World
July 9, 2008
James Mitchell Crow
Pharma goes green to cut costs The pharmaceutical industry's current drive to curb spending is helping to speed the adoption of green chemistry, say experts in the industry. mark for My Articles similar articles
Chemistry World
October 1, 2012
Paul Docherty
Prostaglandin F2I There's been no shortage of grant funding for synthetic chemistry of the prostaglandins, keeping some of the finest minds in organic chemistry engaged over the last five decades. mark for My Articles similar articles
Chemistry World
April 11, 2012
Mico Tatalovic
Croatian scientists call for chemical reagent regulation Prominent Croatian scientists are calling for better regulation of the domestic market for laboratory chemicals and reagents as prices can be as much as 70% higher than in other European countries. mark for My Articles similar articles
Chemistry World
November 28, 2013
What is chemistry? This book is designed to tell the average person all about chemistry, and in a way they can understand. mark for My Articles similar articles
Chemistry World
October 22, 2013
Marie Cote
Oliver Kappe: Freedom to explore Oliver Kappe is professor of chemistry at the University of Graz in Austria. Research in the Kappe group focuses on enabling technologies for synthesis, including microwave and continuous flow methods. mark for My Articles similar articles
Chemistry World
September 24, 2013
Jennifer Newton
Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products. mark for My Articles similar articles
Chemistry World
July 10, 2013
Karl Collins
An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort. mark for My Articles similar articles
Chemistry World
October 12, 2011
Joanne Thomson
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. mark for My Articles similar articles