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Chemistry World December 4, 2009 Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Chemistry World January 8, 2015 Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World August 11, 2011 Hayley Birch |
'Dial a Molecule' Approach Controls Antibiotic Production Scientists have used genetic methods to control the chemical structures of pacidamycin antibiotics produced in bacteria. Their approach allows them to 'dial into' particular molecules, and to generate new pacidamycins. |
Chemistry World July 16, 2009 James Urquhart |
New DNA technique sheds light on ancient populations A new sequencing technique that is cheaper and less wasteful has been used to decode and analyse the mitochondrial genomes of five Neanderthal individuals. |
Geotimes July 2007 Megan Sever |
La Brea Yields Oil-Eating Bacteria Fossils are not the only surprises hidden in the Rancho La Brea tar pits in Los Angeles, Calif. Researchers have recently discovered entire new families of bacteria happily living in the toxic asphalt. |
Chemistry World September 24, 2013 Jennifer Newton |
Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products. |
Technology Research News May 21, 2003 |
DNA sensor changes color University of Rochester researchers have designed a simple, inexpensive sensor that can detect specific sequences of DNA on-the-fly. |
Chemistry World August 11, 2008 |
Yeast Manufacture Morphine Precursor US scientists have developed a way to produce a group of medically important plant compounds in yeast. They say their technique could be used to manufacture drugs including painkillers and new cancer treatments. |
Chemistry World February 22, 2010 Hayley Birch |
Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Technology Research News January 29, 2003 Kimberly Patch |
Data stored in live cells Every type of storage media -- from stone to paper to magnetic disks -- is subject to destruction. Researchers from Pacific Northwest National Laboratory are tapping forces of nature to store information more permanently. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World April 3, 2008 Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World December 6, 2013 Julianne Wyrick |
Crowdsourcing unearths promising anticancer compound Crowdsourcing soil from across the US turned up some interesting fungi with promising medicinal molecules. |
Chemistry World April 27, 2011 Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
Chemistry World July 4, 2008 Emma Davies |
Creating a Second Genetic Code Japanese researchers have made artificial DNA that acts like the real thing, even forming right-handed duplexes with complementary artificial strands. |
Chemistry World July 4, 2010 Hayley Birch |
DNA sticks at flick of switch A new technique that sticks individual DNA molecules to a gold surface works at the flick of an electrochemical switch. |
Chemistry World February 9, 2012 Jennifer Newton |
A new generation of tuberculosis drugs Scientists in India are targeting enzymes responsible for catalysing the formation of bonds to repair nicks in the phosphodiester backbone of DNA - called DNA ligases - to tackle the ever-growing health concern of multi-drug resistant bacteria. |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Technology Research News December 3, 2003 |
Molecule does two-step Duke University researchers have found a way to make a molecule react only when it has been hit by two photons of ultraviolet light, making the molecule a controllable switch. The molecule could eventually be used in optical storage devices and in biochips. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World April 14, 2011 Laura Howes |
DNA origami yields tiny flask A US group of researchers has made a round bottomed flask from folded up DNA with an internal capacity of just 24000nm 3, which would be enough to hold 800,000 molecules of water. |
IEEE Spectrum February 2009 Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Industrial Physicist |
Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Bio-IT World September 2005 Kevin Davies |
Fantastic 454: DNA Sequencing Pyrotechnics In an exciting advance for DNA sequencing technology, a research team at 454 Life Sciences Corp. has essentially sequenced and assembled a bacterial genome sequence based on a mere 4-hour run on the company's proprietary instrument. |
Chemistry World May 20, 2010 Hayley Birch |
The first synthetic cell A chemically synthesised chromosome has for the first time been transplanted into a cell to produce a synthetic bacterium. |
Technology Research News February 11, 2004 |
Scientists brew tree-shaped DNA Researchers from Cornell University have synthesized a new type of DNA that can be used as a nanotechnology building block. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Chemistry World October 14, 2008 Simon Hadlington |
Enzymes hit with double punch US chemists have made a small molecule that simultaneously blocks two key enzymes involved in the growth of cancer cells. |
Chemistry World June 30, 2011 Laura Howes |
Chemically evolved bacteria European scientists have created an Escherichia coli strain with a separate genome using chlorinated DNA. |
Chemistry World May 6, 2009 Phillip Broadwith |
Nano-boxes from DNA origami Danish researchers have made a nano-sized box out of DNA that can be locked or opened in response to 'keys' made from short strands of DNA. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Wired September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
Wired April 21, 2008 Rachel Swaby |
Chromosome, Proteome ... Decoding the DNA of '-omes' The genome alone can't explain how our bodies work. We need to decode a lot of other complex biological systems that regulate how we develop. |
Wired April 2006 Steve Olson |
Bringing Back the Brontosaurus Digging for fossils is for dinosaurs. Today's animal trackers are using genomics to reconstruct, and one day resurrect, the original hot-blooded beast. |
IEEE Spectrum July 2010 Prachi Patel |
Computing the Neanderthal Genome New software helped decode the DNA of our stone-age cousins |
Chemistry World January 30, 2015 Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Scientific American December 19, 2005 |
Lean Gene Machine An ocean bacterium has the most streamlined genome: P. ubique apparently has traded potential for economy in a big way, making its genome the equivalent of a fuel-stingy Volkswagen Beetle, whereas human DNA is more akin to a gas-guzzling Hummer pulling an RV trailer plus a boat. |
Chemistry World February 17, 2013 Simon Hadlington |
Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature. |
Technology Research News October 6, 2004 |
Chip spots DNA electrochemically A microelectrochemical method of reading DNA chips could be used in portable detectors. It could be use practically in two to five years, according to the researchers. |
Chemistry World August 13, 2007 Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Chemistry World November 16, 2011 Simon Hadlington |
Unlocking the secrets of DNA's stiffness Computational chemists believe they have solved one of the puzzles about the stiffness of DNA: how much of the molecule's rigidity is due to electrostatic forces and how much to its physical structure. |
Popular Mechanics April 25, 2008 Erik Sofge |
Inside the Forgotten X Prize--the One That Can Save Your Life An extensive look at the Archon X Prize in Genomics, the $10 million race for a cheap, disease-hunting gene sequencer that could land on your kitchen counter sooner than you think. |