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HHMI Bulletin Aug 2011 |
Seeing is Believing Today, researchers are finding clever ways to deliver long-lasting, healthy genes without triggering a serious immune response. |
Salon.com June 1, 2000 Tabitha M. Powledge |
Gene therapy R.I.P.? When the country's biggest gene therapy institute was ordered to stop testing on humans last week, the action marked the end of an era fraught with dubious claims to success and a mess of unreported adverse effects. |
The Motley Fool March 3, 2011 Ryan McBride |
With Sanofi Buyout of Genzyme, Rare Disease Execs Upbeat About Interest in Their Niche The field might benefit from the increased interest in it among pharmaceutical players. |
BusinessWeek February 10, 2011 Rob Waters |
Sangamo's Bet Against AIDS: Gene Therapy Sangamo's stock has more than doubled since July 6, when the company, with no products on the market, reported success of its gene therapy approach in mice in the journal Nature Biotechnology. |
The Motley Fool July 30, 2007 Brian Orelli |
Another Blow to Gene Therapy The FDA shuts down a clinical trial, tripping up Targeted Genetics and possibly its competitors. A subject in the trial of their gene therapy arthritis medication died shortly after taking the drug. |
Scientific American September 2009 Melinda Wenner |
Gene therapy: An Interview with an Unfortunate Pioneer Lessons learned by James M. Wilson, the scientist behind the first gene therapy death |
BusinessWeek March 6, 2006 Bruce Einhorn |
A Cancer Treatment You Can't Get Here China, with lower regulatory hurdles, is racing to a lead in gene therapy. |
BusinessWeek June 13, 2005 Catherine Arnst |
Biotech, Finally The past 30 years of biological discoveries, insights into the human genome, and exotic chemical manipulation have unleashed a wave of biological drugs, many of them reengineered human proteins. |
Chemistry World July 2010 Hayley Birch |
Special Report: Health breakthroughs of the decade New discoveries have been made with cancer vaccines, genomics, statin drugs, allosteric modulators, and RNA interference during the last decade. |
BusinessWeek September 5, 2005 Capell & Arndt |
Drugs Get Smart Future medicines will more effectively target what ails you by tailoring treatment to your specific genetic profile. Personalized medicine will also help prevent another Vioxx. |
BusinessWeek January 8, 2007 Catherine Arnst |
Decoding Alzheimer's After a century, promising treatments at last - and whispers of a cure. |
AskMen.com Jacob Franek |
Future Cures Almost every disease known to man is under constant research and we can hardly go a day without hearing about some advancement or another. Here are a few diseases for which future cures could be looming on the horizon. |
Pharmaceutical Executive July 30, 2007 |
Tomorrow's Drugs A look at the seven top therapies and technologies vying to deliver the next generation of drugs. |
Pharmaceutical Executive June 1, 2007 |
Thoughtleader: Stephen Sherwin, Cell Genesys Cell Genesys has been able to raise enough capital to gamble on what it CEO believes could be the future's most promising therapies, including gene activation, immunotherapy, and oncolytic virus therapy. |
The Motley Fool September 14, 2006 Brian Lawler |
Close Failure for Genzyme Will Genzyme's Campath get approval? Investors shouldn't hold their breath. |
BusinessWeek March 14, 2005 Arnst & Barrett |
Another Ailing Miracle Drug Biogen's troubles with Tysabri are a setback for immune-system treatments |
Fast Company November 2009 David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Bio-IT World November 14, 2003 Kathy Ordonez |
Targeted Medicine via Molecular Diagnostics Using diagnostics to select and deselect target populations for drug therapy will enable life scientists to make more effective medicines. |
Chemistry World November 5, 2012 Andrew Turley |
Approval for first gene therapy drug Alipogene tiparvovec, marketed as Glybera, has become the first gene therapy drug to win approval in either the US or the EU. |
Pharmaceutical Executive November 1, 2014 Josh Baxt |
2015 Pipeline Report: Burning Bright The science of drug discovery is back on script and the stars are cued up for a new generation of breakthrough therapies. |
BusinessWeek June 13, 2005 John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
BusinessWeek August 26, 2010 Tom Randall |
Cocktails Are Next For Cancer-Drug Makers Taking a cue from the cocktails of drugs that have made AIDS survivable, drugmakers are pursuing combination therapies against cancer. |
The Motley Fool January 26, 2005 John Bluis |
Genzyme Feels the Heat Drug company faces first true competition to its enzyme replacement therapy for Gaucher disease. |
BusinessWeek May 24, 2004 Arlene Weintraub |
Repairing The Engines Of Life Can research into stem cells and other advanced techniques heal ailing hearts and brains? U.S. labs are hamstrung by the federal government. |
Managed Care September 2004 Thomas Morrow |
Orphan Drug Act Treatments Deserve Full Insurance Coverage An important federal law encourages development of drugs for populations so small that the market would otherwise ignore them. Should they not then be covered? |
BusinessWeek April 12, 2004 John Carey |
Gene-Based Therapy: Back To The Couch Recent setbacks show (again) that biotech needs more patience and less ballyhoo |
Managed Care September 2005 Thomas Morrow |
Dual-Treatment Approach to Parkinson's Disease The treatment of Parkinson's disease is complicated. Patients may benefit from a dual approach that uses medical therapy with new innovative treatment systems. |
Wired September 2002 Amanda Griscom |
Take These Genes and Call Me in the Morning Gene vaccines may be relatively new, but they're the logical outgrowth of two familiar strands of medical science. |
Chemistry World February 22, 2011 Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
Wired August 2003 Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Managed Care August 2004 Thomas Morrow |
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. |
Pharmaceutical Executive December 1, 2010 Walter Armstrong |
The Next Wave: Pharm Exec's 2011 Pipeline Report 42 of the best new drugs in development or parked at the FDA |
Pharmaceutical Executive March 1, 2006 Sara Calabro |
Genzyme: The Price of Success Genzyme put patients first, and grew to become a multi-billion-dollar company. But empires don't survive on altruism. |
HHMI Bulletin Nov 2010 |
Fusion genes that drive solid tumors are a new target for cancer therapies The success of Gleevec and related drugs has inspired researchers to step up their hunt for the molecular defects underlying other cancers. |
Pharmaceutical Executive July 1, 2011 Dickmeyer & Rosenbeck |
From Rut to Racetrack Can the pharmaceutical industry deliver on its objective to make cancer a curable, chronic condition? |
The Motley Fool August 10, 2010 Ryan McBride |
Vertex's Telaprevir Clears Hurdle, Could Halve Treatment Times for Hepatitis C Study results are positive. |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
BusinessWeek March 7, 2005 Michael Arndt |
Rewiring The Body First came pacemakers. Now exotic implants are bringing new hope to victims of epilepsy, paralysis, depression, and other diseases. And some of the biggest names in health care are in a scramble to get into the market. |
Managed Care September 2007 |
Gene Discovery May Change Treatments for Hearing Loss Otosclerosis has been traditionally managed with hearing aids and surgery, but a recent discovery may result in development of a biochemical treatment. |
Chemistry World June 2011 |
Breaking through the barrier Getting drug molecules into the brain means crossing the defensive blood-brain barrier. Anthony King investigates how chemists are infiltrating the brain's fortress |
Chemistry World July 2010 Anna Lewcock |
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. |
AskMen.com Jacob Franek |
New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily. |
Chemistry World March 4, 2011 Elinor Richards |
Laser treatment for late-stage cancer Scientists from China, the US and Peru claim to have successfully treated late-stage breast cancer patients using laser immunotherapy to stimulate patients' own immune systems to fight the cancer. |
Managed Care June 2004 Thomas Morrow |
Laronidase Opens Door To Treat Other Rare Disorders The release of alpha-L-iduronidase also demonstrates the wave of future treatments for many other mucopolysaccharidosis (MPS) diseases. |
Pharmaceutical Executive October 1, 2008 |
The other half of an HIV mystery is solved When HIV infects a human immune cell, which of the cell's own genes play a role? |
Chemistry World April 9, 2015 Emma Stoye |
BMS invests in gene therapy Bristol-Myers Squibb has agreed to invest over $100 million in Netherlands-based biotechnology company uniQure, which specializes in gene therapies for cardiovascular diseases. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
The Motley Fool June 2, 2004 Brian Gorman |
New Injection for Genzyme A partnership with Medtronic bolsters Genzyme's myoblast cell therapy program. |
Chemistry World February 24, 2010 James Urquhart |
Buckyball-based gene delivery Japanese researchers have demonstrated effective gene delivery in mice using carbon buckyballs. |
The Motley Fool December 31, 2009 Brian Orelli |
Make Money Even When Drugs Fail Biotech growth potential without as much risk can come from innovations that help drugmakers discover new drugs. |