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Chemistry World March 21, 2013 Phillip Broadwith |
New antimalarial drug class resists resistance Early indications also show that it may take longer for the parasite to develop resistance to the new molecules than it has for existing drugs targeting the same pathway. |
Chemistry World August 18, 2006 Bea Perks |
Resistance is Futile Resistance to malaria drugs poses a serious problem in countries where the disease is endemic. But researchers have now reported the synthesis of a hybrid molecule that combines chloroquine with a molecule that reverses resistance. |
Chemistry World June 17, 2015 James Urquhart |
Promising compound offers single dose knock-out for malaria Ian Gilbert and colleagues, working with the Medicines for Malaria Venture, have found a compound dubbed DDD107498 which kills Plasmodium falciparum -- the species responsible for most dangerous form of malaria. |
Chemistry World July 3, 2006 Mark Peplow |
Drug Screen Reveals Antimalarial Agent A widely-available antihistamine called astemizole could help in the battle against malaria, according to a survey of more than 2,600 drugs in a pharmaceutical library. |
Chemistry World August 7, 2012 Emma Eley |
Improved drugs to treat malarial liver infection Antimalarial drugs with increased in vitro activity have been developed by scientists in Portugal and the US. These novel drugs, called primacins, are active against two stages of malarial infection. |
Chemistry World April 25, 2007 Richard Van Noorden |
Malaria Drug Cures Mice with Single Dose U.S. chemists have adapted a Chinese herbal medicine to create a new generation of antimalarial drugs which could solve some of the current crop's failings. |
Chemistry World April 6, 2010 Phillip Broadwith |
Rousing sleeping sickness research An orally available drug for African sleeping sickness could be on the horizon, say UK scientists who believe that such a drug would improve the lives of more than 50,000 people who are afflicted with the disease. |
HHMI Bulletin Aug 2010 Robert Koenig |
Collaborating Across an Ocean to Stop Malaria Two scholars, one from Mali and one from the United States team up to produce a vaccine for malaria. |
Chemistry World October 18, 2012 Jessica Cocker |
Killing three parasites with one stone Scientists in the US have developed a hybrid drug that is active against malaria, schistosomiasis or hookworm. |
Chemistry World January 18, 2013 Emma Eley |
New method to target malaria Malaria affects millions of people each year; however, no effective vaccines exist. Now, scientists from Spain have discovered a new strategy to target the disease. |
Chemistry World April 2008 Victoria Gill |
Malaria no More? A fresh round of research funding could put an end to the killer disease. |
Chemistry World February 24, 2011 Laura Howes |
Seaweed recruited in fight against malaria Compounds found in seaweed have shown anti-malarial properties, killing even drug-resistant malaria parasites. |
Chemistry World December 15, 2011 |
Eastern promise Yongyuth Yuthavong discusses the challenges that face scientists in Thailand with Kathleen Too. |
The Motley Fool July 12, 2010 Ryan McBride |
Synta Pharma CEO Trumpets New Top Cancer Drug Synta Pharmaceuticals has been climbing back from one of the Boston area's highest-profile clinical trial failures of 2009. |
Chemistry World April 25, 2008 James Mitchell Crow |
Drug Costs Cut on World Malaria Day Swiss pharmaceuticals firm Novartis has announced it will reduce by one fifth the price it charges governments and NGOs for artemisinin-based antimalarial Coartem. |
HHMI Bulletin May 2010 Kendall Powell |
Malaria's Weakness With different approaches, two HHMI researchers land on an enzyme critical to the malaria parasite's destructive ways. |
The Motley Fool July 30, 2010 Brian Orelli |
3 Development-Stage Drugmakers Worth Watching A basket of potential drugs in just one company. |
Chemistry World December 3, 2012 Laura Howes |
Antimalarials should target female parasites The Plasmodium parasite, unlike humans, for example, does not have different genes coding for different sexes. New antimalarials should target the slower evolving female genes, or those that are expressed by both sexes. |
Chemistry World April 27, 2011 Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
Chemistry World May 3, 2012 Akshat Rathi |
Ranbaxy launches new anti-malarial Synriam It is the first recently developed antimalarial that is not based on artemisinin, one of the most effective treatments for malaria, which has begun to suffer from problems with resistance in recent years. |
Scientific American October 2007 Jeffrey D. Sachs |
Ending Malaria Deaths in Africa One of the world s worst killers can be stopped soon if we make the investment. |
The Motley Fool February 16, 2010 Brian Orelli |
For Blockbuster Cancer Drugs, Approvals Are the Easy Part Don't get too excited. As an investor, you can lower your risk by investing in cancer drug companies after a clinical trial success but before an FDA approval, but you'll also reduce your reward. |
Scientific American September 2007 Jeffrey D. Sachs |
Ending Malaria Deaths in Africa One of the world's worst killers can be stopped soon if we make the investment. |
Chemistry World July 15, 2010 Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
BusinessWeek August 26, 2010 Tom Randall |
Cocktails Are Next For Cancer-Drug Makers Taking a cue from the cocktails of drugs that have made AIDS survivable, drugmakers are pursuing combination therapies against cancer. |
Chemistry World March 15, 2011 Sarah Houlton |
Benlysta breaks 50 year Lupus drug drought The first new treatment for lupus erythematosus in half a century has been approved by the US Food and Drug Administration |
The Motley Fool January 21, 2010 Brian Orelli |
The Noble Gesture That Wasn't There may be a motive behind Glaxo helping to develop malaria treatments. |
Chemistry World November 2010 |
Column: In the Pipeline Should drug companies focus on big markets and the blockbuster dream? |
Chemistry World March 2011 |
Column: In the pipeline Drug discovery is an inherently risky business. Derek Lowe tries to balance some of the risk equations |
The Motley Fool February 28, 2011 Brian Orelli |
Rare Diseases, Big Opportunity "Orphan" drugs to keep your eye on. |
BusinessWeek May 13, 2010 Simeon Bennett |
Mobile Phones Fight Africa's Drug Wars New systems that let users dial up to verify antimalarial and other drugs' authenticity could be a major defense against counterfeit meds. |
AskMen.com Jacob Franek |
2008 Medical Science Developments Here are some 2008 medical science developments that might just yield the next big breakthrough. |
The Motley Fool September 26, 2007 Brian Orelli |
4 Platform Drugmakers to Watch Platform drugmakers have the potential to develop multiple drugs for a company. Let's take a look at four companies with good prospects: Abraxis BioScience... DURECT... Halozyme... Flamel Technologies... |
The Motley Fool December 31, 2010 Brian Orelli |
2010 FDA Approvals and a Look Ahead Recent history can help us handicap FDA decisions. |
Chemistry World July 16, 2010 Matt Wilkinson |
Bittersweet victory for GSK's Avandia GlaxoSmithKline has received a muted 'thumbs up' from a US regulatory advisory panel for its much-maligned Type 2 diabetes drug Avandia (rosiglitazone), making it likely the US Food and Drug Administration will allow the UK-based pharma giant to continue selling the drug in the US. |
The Motley Fool December 3, 2010 Brian Orelli |
Merck Smartens Up The acquisition of SmartCells looks like an intelligent move. |
The Motley Fool April 6, 2010 Brian Orelli |
Kill It! Double-Teaming Malaria Malaria vaccine might not make Glaxo and Crucell rich, but the life-saving and PR benefits would be welcome. |
Chemistry World February 9, 2012 Harriet Brewerton |
Pressurizing red blood cells for information Scientists in Canada have developed a method to study the changes in red blood cells caused by the most common malaria parasite Plasmodium falciparum. |
HHMI Bulletin Nov 2010 |
Scientists are targeting surface proteins to battle disease. Now that genomic analyses have identified the genes that express surface proteins, scientists are focusing on how pathogens detect attacks from the human immune system and quickly change their coats. |
The Motley Fool May 21, 2010 Brian Orelli |
And You Thought Biotech Was High-Risk, High-Reward Large clinical trials make cardiovascular drugs risky, but the rewards are there, too. |
BusinessWeek June 16, 2011 Langreth & Cortez |
When Two Cancer Drugs Are Better Than One Drugmakers are collaborating to test combinations of genetically targeted cancer drugs in hopes of boosting survival rates. |
Chemistry World March 13, 2013 Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
Chemistry World January 30, 2015 Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Chemistry World February 12, 2014 Graham Wynne |
Introduction to biological and small molecule drug research and development This text, edited by Ganellin and others, will be of particular interest both to the medicinal chemist who is looking to increase their knowledge beyond the small molecules area, and those with experience in the biologics field. |
The Motley Fool January 29, 2010 Brian Orelli |
How to Make Billions of Dollars Without Really Trying Lackluster Alzheimer's drugs have been doing it for years. |
Chemistry World June 2008 Sarah Houlton |
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success |
Chemistry World April 25, 2013 Phillip Broadwith |
Portable detector shines light on fake drugs The CD-3 counterfeit detection device uses a variety of different wavelengths of light to visually compare tablets, capsules and their packaging with genuine reference samples. |
Chemistry World September 10, 2007 Lewis Brindley |
Taking the Sting Out of Malaria Scientists have identified sugar chains lining the mosquito's gut that the malaria parasite latches onto to infect the insect. |
Chemistry World March 27, 2013 Eugene Gerden |
Russian investment vehicle sets sights on innovative drugs Russian state-owned nanotechnology giant Rusnano is hoping to break into the pharmaceutical sector with sizeable investments in firms seeking to produce innovative drugs. |
Chemistry World April 2011 |
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. |