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Chemistry World
March 21, 2013
Phillip Broadwith
New antimalarial drug class resists resistance Early indications also show that it may take longer for the parasite to develop resistance to the new molecules than it has for existing drugs targeting the same pathway. mark for My Articles similar articles
Chemistry World
August 18, 2006
Bea Perks
Resistance is Futile Resistance to malaria drugs poses a serious problem in countries where the disease is endemic. But researchers have now reported the synthesis of a hybrid molecule that combines chloroquine with a molecule that reverses resistance. mark for My Articles similar articles
Chemistry World
June 17, 2015
James Urquhart
Promising compound offers single dose knock-out for malaria Ian Gilbert and colleagues, working with the Medicines for Malaria Venture, have found a compound dubbed DDD107498 which kills Plasmodium falciparum -- the species responsible for most dangerous form of malaria. mark for My Articles similar articles
Chemistry World
July 3, 2006
Mark Peplow
Drug Screen Reveals Antimalarial Agent A widely-available antihistamine called astemizole could help in the battle against malaria, according to a survey of more than 2,600 drugs in a pharmaceutical library. mark for My Articles similar articles
Chemistry World
August 7, 2012
Emma Eley
Improved drugs to treat malarial liver infection Antimalarial drugs with increased in vitro activity have been developed by scientists in Portugal and the US. These novel drugs, called primacins, are active against two stages of malarial infection. mark for My Articles similar articles
Chemistry World
April 25, 2007
Richard Van Noorden
Malaria Drug Cures Mice with Single Dose U.S. chemists have adapted a Chinese herbal medicine to create a new generation of antimalarial drugs which could solve some of the current crop's failings. mark for My Articles similar articles
Chemistry World
April 6, 2010
Phillip Broadwith
Rousing sleeping sickness research An orally available drug for African sleeping sickness could be on the horizon, say UK scientists who believe that such a drug would improve the lives of more than 50,000 people who are afflicted with the disease. mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Robert Koenig
Collaborating Across an Ocean to Stop Malaria Two scholars, one from Mali and one from the United States team up to produce a vaccine for malaria. mark for My Articles similar articles
Chemistry World
October 18, 2012
Jessica Cocker
Killing three parasites with one stone Scientists in the US have developed a hybrid drug that is active against malaria, schistosomiasis or hookworm. mark for My Articles similar articles
Chemistry World
January 18, 2013
Emma Eley
New method to target malaria Malaria affects millions of people each year; however, no effective vaccines exist. Now, scientists from Spain have discovered a new strategy to target the disease. mark for My Articles similar articles
Chemistry World
April 2008
Victoria Gill
Malaria no More? A fresh round of research funding could put an end to the killer disease. mark for My Articles similar articles
Chemistry World
February 24, 2011
Laura Howes
Seaweed recruited in fight against malaria Compounds found in seaweed have shown anti-malarial properties, killing even drug-resistant malaria parasites. mark for My Articles similar articles
Chemistry World
December 15, 2011
Eastern promise Yongyuth Yuthavong discusses the challenges that face scientists in Thailand with Kathleen Too. mark for My Articles similar articles
The Motley Fool
July 12, 2010
Ryan McBride
Synta Pharma CEO Trumpets New Top Cancer Drug Synta Pharmaceuticals has been climbing back from one of the Boston area's highest-profile clinical trial failures of 2009. mark for My Articles similar articles
Chemistry World
April 25, 2008
James Mitchell Crow
Drug Costs Cut on World Malaria Day Swiss pharmaceuticals firm Novartis has announced it will reduce by one fifth the price it charges governments and NGOs for artemisinin-based antimalarial Coartem. mark for My Articles similar articles
HHMI Bulletin
May 2010
Kendall Powell
Malaria's Weakness With different approaches, two HHMI researchers land on an enzyme critical to the malaria parasite's destructive ways. mark for My Articles similar articles
The Motley Fool
July 30, 2010
Brian Orelli
3 Development-Stage Drugmakers Worth Watching A basket of potential drugs in just one company. mark for My Articles similar articles
Chemistry World
December 3, 2012
Laura Howes
Antimalarials should target female parasites The Plasmodium parasite, unlike humans, for example, does not have different genes coding for different sexes. New antimalarials should target the slower evolving female genes, or those that are expressed by both sexes. mark for My Articles similar articles
Chemistry World
April 27, 2011
Carol Stanier
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. mark for My Articles similar articles
Chemistry World
May 3, 2012
Akshat Rathi
Ranbaxy launches new anti-malarial Synriam It is the first recently developed antimalarial that is not based on artemisinin, one of the most effective treatments for malaria, which has begun to suffer from problems with resistance in recent years. mark for My Articles similar articles
Scientific American
October 2007
Jeffrey D. Sachs
Ending Malaria Deaths in Africa One of the world s worst killers can be stopped soon if we make the investment. mark for My Articles similar articles
The Motley Fool
February 16, 2010
Brian Orelli
For Blockbuster Cancer Drugs, Approvals Are the Easy Part Don't get too excited. As an investor, you can lower your risk by investing in cancer drug companies after a clinical trial success but before an FDA approval, but you'll also reduce your reward. mark for My Articles similar articles
Scientific American
September 2007
Jeffrey D. Sachs
Ending Malaria Deaths in Africa One of the world's worst killers can be stopped soon if we make the investment. mark for My Articles similar articles
Chemistry World
July 15, 2010
Matt Wilkinson
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. mark for My Articles similar articles
BusinessWeek
August 26, 2010
Tom Randall
Cocktails Are Next For Cancer-Drug Makers Taking a cue from the cocktails of drugs that have made AIDS survivable, drugmakers are pursuing combination therapies against cancer. mark for My Articles similar articles
Chemistry World
March 15, 2011
Sarah Houlton
Benlysta breaks 50 year Lupus drug drought The first new treatment for lupus erythematosus in half a century has been approved by the US Food and Drug Administration mark for My Articles similar articles
The Motley Fool
January 21, 2010
Brian Orelli
The Noble Gesture That Wasn't There may be a motive behind Glaxo helping to develop malaria treatments. mark for My Articles similar articles
Chemistry World
November 2010
Column: In the Pipeline Should drug companies focus on big markets and the blockbuster dream? mark for My Articles similar articles
Chemistry World
March 2011
Column: In the pipeline Drug discovery is an inherently risky business. Derek Lowe tries to balance some of the risk equations mark for My Articles similar articles
The Motley Fool
February 28, 2011
Brian Orelli
Rare Diseases, Big Opportunity "Orphan" drugs to keep your eye on. mark for My Articles similar articles
BusinessWeek
May 13, 2010
Simeon Bennett
Mobile Phones Fight Africa's Drug Wars New systems that let users dial up to verify antimalarial and other drugs' authenticity could be a major defense against counterfeit meds. mark for My Articles similar articles
AskMen.com
Jacob Franek
2008 Medical Science Developments Here are some 2008 medical science developments that might just yield the next big breakthrough. mark for My Articles similar articles
The Motley Fool
September 26, 2007
Brian Orelli
4 Platform Drugmakers to Watch Platform drugmakers have the potential to develop multiple drugs for a company. Let's take a look at four companies with good prospects: Abraxis BioScience... DURECT... Halozyme... Flamel Technologies... mark for My Articles similar articles
The Motley Fool
December 31, 2010
Brian Orelli
2010 FDA Approvals and a Look Ahead Recent history can help us handicap FDA decisions. mark for My Articles similar articles
Chemistry World
July 16, 2010
Matt Wilkinson
Bittersweet victory for GSK's Avandia GlaxoSmithKline has received a muted 'thumbs up' from a US regulatory advisory panel for its much-maligned Type 2 diabetes drug Avandia (rosiglitazone), making it likely the US Food and Drug Administration will allow the UK-based pharma giant to continue selling the drug in the US. mark for My Articles similar articles
The Motley Fool
December 3, 2010
Brian Orelli
Merck Smartens Up The acquisition of SmartCells looks like an intelligent move. mark for My Articles similar articles
The Motley Fool
April 6, 2010
Brian Orelli
Kill It! Double-Teaming Malaria Malaria vaccine might not make Glaxo and Crucell rich, but the life-saving and PR benefits would be welcome. mark for My Articles similar articles
Chemistry World
February 9, 2012
Harriet Brewerton
Pressurizing red blood cells for information Scientists in Canada have developed a method to study the changes in red blood cells caused by the most common malaria parasite Plasmodium falciparum. mark for My Articles similar articles
HHMI Bulletin
Nov 2010
Scientists are targeting surface proteins to battle disease. Now that genomic analyses have identified the genes that express surface proteins, scientists are focusing on how pathogens detect attacks from the human immune system and quickly change their coats. mark for My Articles similar articles
The Motley Fool
May 21, 2010
Brian Orelli
And You Thought Biotech Was High-Risk, High-Reward Large clinical trials make cardiovascular drugs risky, but the rewards are there, too. mark for My Articles similar articles
BusinessWeek
June 16, 2011
Langreth & Cortez
When Two Cancer Drugs Are Better Than One Drugmakers are collaborating to test combinations of genetically targeted cancer drugs in hopes of boosting survival rates. mark for My Articles similar articles
Chemistry World
March 13, 2013
Ned Stafford
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. mark for My Articles similar articles
Chemistry World
January 30, 2015
Rebecca Trager
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria mark for My Articles similar articles
Chemistry World
February 12, 2014
Graham Wynne
Introduction to biological and small molecule drug research and development This text, edited by Ganellin and others, will be of particular interest both to the medicinal chemist who is looking to increase their knowledge beyond the small molecules area, and those with experience in the biologics field. mark for My Articles similar articles
The Motley Fool
January 29, 2010
Brian Orelli
How to Make Billions of Dollars Without Really Trying Lackluster Alzheimer's drugs have been doing it for years. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
April 25, 2013
Phillip Broadwith
Portable detector shines light on fake drugs The CD-3 counterfeit detection device uses a variety of different wavelengths of light to visually compare tablets, capsules and their packaging with genuine reference samples. mark for My Articles similar articles
Chemistry World
September 10, 2007
Lewis Brindley
Taking the Sting Out of Malaria Scientists have identified sugar chains lining the mosquito's gut that the malaria parasite latches onto to infect the insect. mark for My Articles similar articles
Chemistry World
March 27, 2013
Eugene Gerden
Russian investment vehicle sets sights on innovative drugs Russian state-owned nanotechnology giant Rusnano is hoping to break into the pharmaceutical sector with sizeable investments in firms seeking to produce innovative drugs. mark for My Articles similar articles
Chemistry World
April 2011
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. mark for My Articles similar articles