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Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Chemistry World October 13, 2015 Simon Hadlington |
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
Chemistry World April 2, 2009 Ned Stafford |
Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Industrial Physicist Aug/Sep 2003 Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Technology Research News September 24, 2003 Kimberly Patch |
Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command. |
Chemistry World February 8, 2006 Jon Evans |
To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space. |
Chemistry World May 15, 2006 Jon Evans |
Selective DNA Crystals A molecular biologist has developed a molecular sieve using a DNA crystal with nanoscale channels. |
Bio-IT World May 19, 2004 |
Special Delivery TAT tagging has aroused keen interest in biotech. |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
Reactive Reports Issue 54 David Bradley |
Hula-Hoop DNA Amplification Periodic nanostructures made of gold nanoparticles and long DNA strands with repeated sequences have been prepared by using a technique known as "rolling circle amplification" or the "hula-hoop" technique. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World December 23, 2015 |
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. |
Chemistry World September 2, 2009 Phillip Broadwith |
Shining a light on DNA-binding drugs in living cells German researchers have used standard circular dichroism spectroscopy to probe interactions between drug molecules and DNA within living cells. |
Chemistry World July 4, 2010 Hayley Birch |
DNA sticks at flick of switch A new technique that sticks individual DNA molecules to a gold surface works at the flick of an electrochemical switch. |
Chemistry World October 15, 2009 Simon Hadlington |
Optical conveyor belt gathers up molecules Researchers in Germany have developed a novel way to 'round up' biological molecules that are freely suspended in solution and trap them in a confined space using nothing more than light. |
Bio-IT World April 16, 2004 Robert Frederickson |
Trial Separations Protein separation through the digital ProteomeChip microchip takes merely minutes, resulting in significantly increased productivity. |
Chemistry World March 15, 2010 James Urquhart |
All aboard the DNA nanotube Cargo-carrying DNA nanotubes that can rapidly release their load on demand have been made for the first time by Canadian researchers. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
Chemistry World May 6, 2009 Phillip Broadwith |
Nano-boxes from DNA origami Danish researchers have made a nano-sized box out of DNA that can be locked or opened in response to 'keys' made from short strands of DNA. |
Chemistry World September 6, 2013 Melissae Fellet |
Unravelling stereochemistry via mass spectrometry Researchers have used mass spectrometry to determine the stereochemistry of a prototypical chiral molecule, CHBrClF. |
Chemistry World September 3, 2013 William Bergius |
Better separations with more permeable membranes There is usually a trade-off between selectivity and liquid permeability when making an ultrafiltration membrane but new research from scientists in the US suggests this doesn't have to be the case. |
Scientific American June 2005 JR Minkel |
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Technology Research News August 10, 2005 |
DNA process stamps patterns DNA's ability to connect matching strands is at the heart of a stamp that promises to bring mass production to the nanoscale. |
Chemistry World May 2011 |
Column: In the pipeline Molecular biology, physics, materials science, physiology, even pure mathematics is a neighbor, and these neighbors are usually reached through a zone of interdisciplinary stuff that's rather hard to define. So who counts as a chemist? |
Chemistry World December 2007 Derek Lowe |
Column: In the Pipeline The challenge of biologics. |
Technology Research News December 3, 2003 |
Molecule does two-step Duke University researchers have found a way to make a molecule react only when it has been hit by two photons of ultraviolet light, making the molecule a controllable switch. The molecule could eventually be used in optical storage devices and in biochips. |
Chemistry World February 12, 2014 Manisha Lalloo |
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. |
Technology Research News March 12, 2003 |
RNA forms nanomotor Researchers from Purdue University have constructed a tiny motor from DNA and RNA molecules. The device, fueled by ATP, which powers our own movements, could eventually power nanomachines. |
Industrial Physicist |
Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. |
Technology Research News December 3, 2003 Kimberly Patch |
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. |
PC World February 1, 2002 Kuriko Miyake |
Olympus Unveils DNA Computer Rather than relying on a microprocessor, computer runs on reactions between fragments of DNA... |
Chemistry World August 22, 2008 Hayley Birch |
Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes. |
D-Lib February 2001 |
Molecule of the Month The Molecule of the Month website is based at the University of Bristol in the United Kingdom. As well as being a site containing many interesting chemical facts, the site provides a good example of the way the web can be used to create a truly worldwide database of information... |
Chemistry World January 28, 2015 Emma Stoye |
Tiny volcanic cracks 'incubated' ancient DNA Tiny pores within volcanic rocks on ancient Earth may have provided the ideal conditions for replicating molecules, and could also have driven the evolution of longer and longer genetic sequences, researchers in Germany have shown. |