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Chemistry World October 12, 2015 Andy Extance |
'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say. |
Chemistry World May 6, 2008 James Mitchell Crow |
Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs. |
Chemistry World March 16, 2014 Simon Hadlington |
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. |
Chemistry World August 2, 2011 Phillip Broadwith |
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. |
Chemistry World October 27, 2014 Tim Wogan |
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. |
Chemistry World October 9, 2006 Michael Gross |
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. |
Chemistry World January 19, 2010 Simon Hadlington |
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. |
Chemistry World April 2009 Philip Ball |
Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth |
Chemistry World September 12, 2010 Mike Brown |
Comet shockwaves helped stimulate life on Earth The shock waves caused as comets hit the early Earth could have helped promote the formation of amino acids and the early building blocks of life, say US researchers. |
Chemistry World June 4, 2008 Lewis Brindley |
Peptide printer goes into overdrive Synthesizing arrays of short peptides could soon be as easy as printing them out - thanks to the development of a modified laser printer that uses amino acids instead of colored ink. |
Chemistry World March 30, 2011 Hayley Birch |
Amino acid synthesis hints at how the genetic code expanded The detailed pathway for the biosynthesis of pyrrolysine - the 22nd and latest amino acid to be discovered - has been outlined by US researchers. |
Chemistry World September 7, 2014 Michael Gross |
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature. |
Chemistry World July 26, 2007 Richard Van Noorden |
Shortcut Protein Synthesis Ditches Amino Acids Chinese chemists have demonstrated a speedy way to make polypeptides by avoiding the costly tedium of linking together amino acids. |
Chemistry World October 8, 2008 Sarah Houlton |
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. |
Prepared Foods June 1, 2005 Marcia A. Wade |
Extended Shelflife: Bar None A partially hydrolyzed premium whey protein isolate designed to control water migration can extend the shelflife of nutrition bars -- up to a year, in some cases. |
Chemistry World June 1, 2012 Simon Hadlington |
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. |
Chemistry World October 10, 2012 Phillip Broadwith |
Taming erythropoietin through synthesis US researchers have produced a fully synthetic version of erythropoietin, the glycoprotein responsible for regulating blood cell production. |
Pharmaceutical Executive November 1, 2006 |
Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before. |
Chemistry World August 20, 2008 |
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface. |
Chemistry World August 28, 2011 Simon Hadlington |
Synthetic self-assembling collagen for tissue engineering US researchers have succeeded in making the most realistic synthetic collagen to date. |
Chemistry World October 27, 2006 Richard Van Noorden |
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Bio-IT World December 10, 2002 Kevin Davies |
Do Try This @ Home In the most impressive sign of distributed computing's awesome potential in biology thus far -- at least in peer-review literature -- researchers have simulated the folding of a mini-protein on a microsecond timescale. |
Chemistry World June 17, 2013 Eleanor Merritt |
Switching chirality in amino acids An international team of scientists has developed a purely chemical approach to interconvert L- and D-amino acids. This method could rival enzymatic routes used in industry, and enable cheaper production of some pharmaceuticals. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World December 21, 2006 Henry Nicholls |
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. |
Chemistry World April 29, 2013 Caryl Richards |
Protein origami sets scene for designer structures A world first in the art of protein origami has been attained with a novel method of folding a polypeptide chain into a three-dimensional tetrahedron. |
Chemistry World July 2, 2014 Tim Wogan |
Miller's forgotten experiments point to primitive protein genesis Stanley Miller's experiments are still adding to our understanding of prebiotic Earth. |
Chemistry World September 30, 2014 Kirsty Muirhead |
Mirror peptides hitch a lift into the cell Scientists in the US have developed a method for successfully transporting chemotherapeutic d-peptides into the cell cytosol. |
Chemistry World October 18, 2006 Michael Gross |
Death Sentences for Microbes Researchers have used methods borrowed from linguistics in the hunt for new antimicrobial agents. |
Chemistry World January 10, 2013 Laura Howes |
Rotaxane mimics ribosome to spin out peptides The field of molecular machines has taken a new bio-inspired turn to assemble another molecule, in this case linking up individual amino acids into a peptide. |
Bio-IT World June 12, 2002 Karen Hopkin |
Computational Biologists Join the Fold CASP5 competitors compare the best algorithms for modeling the 3-D structure of proteins -- an exercise that could lead to new insights into the pathogenesis and treatment of disease. |
Investment Advisor November 2005 Jeff Joseph |
Hedgeworld Hedge Fund Focus: The Roles of Alpha and Beta Acknowledging the elusive nature of alpha is critical to hedge fund and absolute return investors, particularly because most think of alpha as the primary (if not the exclusive) source of hedge fund returns. But this may be an erroneous assumption. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World October 26, 2006 Victoria Gill |
Volcanoes Reveal the Secret of the Origin of Life Life began with a chemical reaction under the sea over four billion years ago. That is the claim of a German scientist whose team has recreated a crucial part of the reaction, synthesizing all the necessary ingredients for a living organism. |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Chemistry World March 19, 2014 Emma Stoye |
Molecular drill bits attack tuberculosis Peptides that punch through bacterial cell walls while leaving human cells unharmed could open up new ways to tackle antibiotic resistance, say researchers in the US. |
The Motley Fool November 20, 2006 Dan Caplinger |
It's All Greek to Me Finance's unique combination of mathematical and social sciences makes the field a linguistic battleground among academics. As ways to express financial concepts, alpha and beta are relatively simple. |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |
Prepared Foods October 1, 2005 |
Ask the Expert: Whey Proteins and Nutrition Bars A food technologist addresses how manufacturers can use whey proteins to extend the shelf life of nutrition bars. |
Financial Planning February 1, 2007 David E. Adler |
High Net Worth: Alpha-Beta Investing This institutional strategy is starting to make inroads among high-net-worth managers. |
Chemistry World April 8, 2008 Mark Peplow |
Meteorite Source for Life's Handedness Scientists have long speculated that life's preference for left-handed amino acids may have been triggered by compounds brought to Earth by meteorites. Now they've shown exactly how two crucial steps in this process could happen. |
Financial Planning April 1, 2011 Suzanne McGee |
Chasing Alpha With investment strategists and pundits predicting a long period of sluggish returns that may not make it out of the single digits, there is every reason for advisors to intensify their quest for alpha. But alpha is both hard to define and harder to find. |
Chemistry World June 2009 Michael Gross |
Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun |
Geotimes October 2004 Laura Stafford |
Volcanic gas and early life Researchers have combined carbonyl sulfide with free amino acids in a reaction that created di-, tri- and tetra-peptides. The experiment was conducted under a variety of conditions meant to simulate Earth's early atmosphere. |
Financial Planning November 1, 2006 Craig L. Israelsen |
Alpha Goes Abroad Excess returns turn up in overseas large-cap value funds. |
Chemistry World June 16, 2014 James Urquhart |
Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand. |
Wall Street & Technology May 15, 2006 Larry Tabb |
Strolling With My Alpha How does portable alpha impact the investment management business? This strategy turns portfolio managers into asset allocators. Instead of picking stocks, or companies, they pick inexpensive indices and choose expensive hedge funds. |