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Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
ONLINE Nov/Dec 2008 Suzanne Sabroski |
From Concept to Content: The Genesis of USGENE Last year a groundbreaking database known as USGENE was released on STN International, a service of FIZ Karlsruhe and Chemical Abstracts Service (CAS). USGENE allows searchers to perform freedom-to-operate, prior art, validity, and infringement patent sequence searches. |
Wired August 2000 Jennifer Hillner |
Area 22 The inside story of the first fully sequenced chromosome. |
Salon.com June 27, 2000 Tabitha M. Powledge |
Book of life? Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not. |
Bio-IT World December 10, 2002 Rotem Sorek |
Alternative Splicing: Listen to the Mouse The completed mouse genome may help to finally pin down the size of the transcriptome. |
Bio-IT World September 2005 Kevin Davies |
Fantastic 454: DNA Sequencing Pyrotechnics In an exciting advance for DNA sequencing technology, a research team at 454 Life Sciences Corp. has essentially sequenced and assembled a bacterial genome sequence based on a mere 4-hour run on the company's proprietary instrument. |
Bio-IT World November 12, 2002 Davies et al. |
John Craig Venter Unvarnished The former Celera CEO talks about that company's politics, the future of sequencing technology, and his own genome. |
Salon.com May 1, 2000 Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Bio-IT World November 12, 2002 Kevin Davies |
DNA for Dummies? The journal Nature Genetics has just published a user's guide to the human genome -- and none too soon. |
Salon.com April 24, 2000 Mark Compton |
Lean, green gene-counting machine Incyte CEO Roy Whitfield gives biotech investors and patent critics a few lessons on genomic research. |
Information Today August 4, 2011 |
Elsevier Introduces Genome Viewer The Genome Viewer is a SciVerse application that displays detailed gene or genomic sequence information on the genes mentioned in an article. |
Bio-IT World May 2006 Kevin Davies |
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. |
Bio-IT World June 2005 Maureen McDonough |
Celera Releases Genome Data In a decision that essentially marks the end of the genome wars, Celera Genomics will release its formerly proprietary human, mouse, and rat genome sequences to the public domain. |
Bio-IT World September 11, 2003 Melissa Kruse |
Soul Searching Two years ago, 2,792 lives were lost in the collapse of the World Trade Center. While rescuers labored night and day to recover the bodies, a small Michigan software company set about salvaging their identities. |
Bio-IT World February 10, 2003 Kevin Davies |
With a Click of the Mouse What do Eminem and Mus musculus have in common? About 30,000 genes, for a start. The author mulls over the second mammalian genome. |
Information Today September 17, 2007 |
Thomson Scientific Introduces Data Platform for Biological Researchers Thomson Scientific announced the release of BONDplus, an integrated, Web-based data platform for biological researchers. |
BusinessWeek June 13, 2005 John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
Salon.com February 13, 2001 Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
Bio-IT World October 9, 2002 Kevin Davies |
Cracking the 'Druggable Genome' How many potential drug targets are encoded in the human genome? It is a crucial question for every biopharma business. |
Reason Aug/Sep 2000 Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
BusinessWeek May 9, 2005 John Carey |
Dr. Francis S. Collins: On The Trail Of Disease Genes Collins is leading the search for DNA variations that can result in illnesses. |
HHMI Bulletin May 2012 Sarah C. P. Williams |
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. |
IEEE Spectrum July 2010 Prachi Patel |
Computing the Neanderthal Genome New software helped decode the DNA of our stone-age cousins |
Wired December 2002 Douglas McGray |
Supermicrobe Man First Craig Venter cracked the human genome. Now he wants to sequence the ocean and save the world. |
Bio-IT World April 2006 Karen Hopkin |
AGBT Meeting Puts Genome Advances Front and Center If the presentations at February's Advances in Genome Biology and Technology (AGBT) are any indication, the race to generate fresh approaches to produce more sequence for less is far from over -- and looks to be heating up. |
Bio-IT World December 10, 2002 |
Craig Venter Unvarnished (part II) The former Celera CEO covers privacy, ESTs, and his new research institutes. |
Bio-IT World May 2006 Kevin Davies |
Ashburner Receives Bioinformatics Benjamin Franklin Award A noted Drosophila researcher who helped lead the project to sequence the fruit fly genome in the late 1990s, Michael Ashburner was lauded for his steadfast championing of open-source resources for the genetics and informatics communities. |
Bio-IT World November 12, 2002 Beth E. Arnold |
Navigating Gene Patent Minefields As the number of gene-related patents soars, so do the chances of patent infringement. Here are tips to avoid a costly misstep in this legal minefield. |
Chemistry World July 13, 2011 Hayley Birch |
Naked mole-rat genome holds clue to beating cancer The recently published draft sequence of the naked mole-rat genome promises to reveal the secrets of its long and remarkably cancer-free existence, potentially providing new targets for anti-cancer drugs. |
Bio-IT World July 14, 2004 Malorye A. Branca |
The Maven of Microarrays Affymetrix Research Institute's CEO, Stephen Fodor, discusses building a tech business without a blueprint |
Fast Company November 2009 David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Bio-IT World January 21, 2005 Kevin Davies |
Simulated Shades of Jurassic Park? Bioinformatics researchers have re-created part of the genome sequence of an ancestral mammal that lived 70 million to 80 million years ago. |
Bio-IT World June 12, 2002 Kevin Davies |
Variations on a Theme Researchers at Genaissance Pharmaceuticals have outlined the path to creating a comprehensive map of human genomic variation that should ultimately reveal the genetic underpinnings of common diseases. |
BusinessWeek October 23, 2008 John Carey |
Reading the Entire Genetic Code Pioneers such as 23andMe and Navigenics use snips of genes to make medical predictions. Now new tools from more start-ups are on the horizon. |
Fast Company September 2000 John Ellis |
The Secret of Life The mapping of the human genome, says Craig Venter, will change science, research, medicine, politics, health insurance, and the way biology looks at the last 3 billion years of evolution. And that's just the beginning. |
Bio-IT World November 2005 Khaleeli & Fernandez |
Patent Prosecution and Enforcement in Pharmacogenomics Patenting the composition of an isolated nucleic acid sequence, an isolated protein, and small molecules is possible, but there are challenges claiming that they resulted from pharmacogenomic research. |
The Motley Fool August 12, 2009 Brian Orelli |
The Next Big Thing Is Not Right in Front of You Perhaps the fastest evolving technology right now is found in DNA sequencing. |
Bio-IT World October 9, 2002 Malorye Branca |
The Path to Personalized Medicine The tactics have changed, sometimes dramatically, but hints of the promise of pharmacogenomics are finally starting to trickle in from studies of asthma, cancer, and drug response. |
Bio-IT World Dec 2006/Jan 2007 Kevin Davies |
The One Percent Difference New research reveals a shocking new layer of human genome variation with profound implications for the future of genomic analysis and personalized medicine. |
Bio-IT World October 2005 Dennis A. Gilbert |
The DNA Sequencing Race: From Sprint to Marathon To create faster, cheaper, and better solutions for DNA analysis, we must remain committed to improving both current and new sequencing technologies. Research that just a short while ago might have been considered too complex, too expensive, or just inconceivable is now well within our grasp. |
Scientific American July 2008 Christine Soares |
Looking at Yesterday's Genes for Tomorrow's Cures Resurrected "jumping gene" could deliver DNA. |
Bio-IT World November 12, 2002 Paula Campbell Evans |
Patently More Difficult The PTO has targeted gene patents with new application guidelines. Here's what they mean and how biotech companies can satisfy them. |
IEEE Spectrum March 2013 Eliza Strickland |
The Gene Machine and Me Ion Torrent's chip-based genome sequencer is cheap, fast, and poised to revolutionize medicine |
Bio-IT World November 14, 2003 Julia Boguslavsky |
Genome Center in a Box Scientists at 454 Life Sciences developed an integrated end-to-end instrument that performs hundreds of thousands of reactions in parallel -- from sample preparation, amplification, and sequencing to data storage and bioinformatics. |
Bio-IT World Jul/Aug 2006 Kate McDonald |
The Next Generation in Sequencing Is SOLiD Applied Biosystems has completed the acquisition of genetic analysis company Agencourt Personal Genomics for $120 million, and hopes to bring the company's novel next-generation sequencing technology to market next year. |
Reason August 2002 Charles Paul Freund |
DNA Dough-Re-Mi A pretty girl may be like a melody, but the music of her DNA could have biotech companies whistling all the way to the bank. An executive at Maxygen, a California biotech firm, has suggested that if DNA sequences were converted to digital music they could be copyrighted as works of art. |
Chemistry World September 14, 2011 David Bradley |
Brewing up Synthetic Yeast Yeast with synthetic genomes could be very useful for medicinal chemists and drug companies. |
Chemistry World July 21, 2011 James Mitchell Crow |
Sequencing Chip Decodes DNA Proton by Proton Technology that can directly detect the chemical reaction as a single nucleotide adds to the end of a growing strand of DNA is about to slash the cost of genome sequencing, its inventors say. |
Bio-IT World November 19, 2004 Kevin Davies |
The Book on Bioinformatics Research director David Mount talks about his new book "Bioinformatics: Sequence and Genome Analysis," sequence analysis, and teaching bioinformatics |