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Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World April 2007 Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World February 2007 Dylan Stiles |
Bench Monkey There's a recurring problem in synthesis where functional groups in a molecule are prone to unwanted side reactions. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World October 12, 2011 Joanne Thomson |
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. |
Chemistry World September 4, 2012 Derek Lowe |
Light in the Lab We organic chemists do terrible things to our molecules. How about dissolving the starting materials up in a flask, shining a light into the mixture and coming back later to find it transformed into your product? That's photochemistry. |
HHMI Bulletin Nov 2011 Sarah C.P. Williams. |
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. |
Chemistry World October 27, 2006 Richard Van Noorden |
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. |
Information Today July 2, 2015 |
Thieme Chemistry Updates Synthetic Organic Chemistry Resource Thieme Chemistry rolled out the newest release of its Science of Synthesis 4.1, which is a full-text resource for methods and experimental procedures in synthetic organic chemistry. |
Chemistry World April 11, 2014 |
The sultan of synthesis Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers |
Chemistry World June 19, 2013 John Hayward |
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. |
Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
Chemistry World November 2, 2015 |
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health. |
Chemistry World July 10, 2013 Marie Cote |
Never shut down another person's ideas Vy Dong is a professor at the University of California at Irvine, US. Her group investigates better tools for organic synthesis, including new reagents, catalysts and strategies. |
Chemistry World September 18, 2013 Phillip Broadwith |
Service with a smile Contract organic synthesis is a competitive business. Service companies in China and India offer their skills at prices it can be difficult for western firms to compete with. So how does a company stand out from the crowd? |
Chemistry World March 2012 |
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug |
Chemistry World November 12, 2014 Iain A Smellie |
Organic chemistry: structure, mechanism and synthesis This book contains all the key concepts one would expect in a good core organic chemistry textbook. The content also extends towards biochemistry and molecular biology. |
Chemistry World January 11, 2013 Marie Cote |
Following her passion Veronique Gouverneur is professor of chemistry at the University of Oxford, UK. She investigates fluorine chemistry and is working on developing novel synthetic methodologies for the preparation of fluorinated targets. |
Chemistry World August 1, 2013 James Urquhart |
Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
Chemistry World November 1, 2007 Richard Van Noorden |
Step Change for Organic Synthesis US chemists discovered how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups. |
Chemistry World May 15, 2007 Richard Van Noorden |
New Research Centres for UK Chemistry Two research centres hoping to add new dimensions to UK chemistry were officially launched last week. |
Chemistry World August 28, 2015 Derek Lowe |
A risky business How much of a risk is it to work in an organic chemistry lab? Back when I was first beginning bench work in graduate school, I was home during the holidays and telling some lab stories. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World July 2007 Dylan Stiles |
Opinion: Bench Monkey Synthesizing molecules that force atoms into bizarre contortionist acts is the only way to learn. |
Chemistry World October 2011 Derek Lowe |
Column: In the Pipeline Research chemistry has hazards, some of them potentially fatal, and attention to safety is an essential part of working in the field. The hard part comes when you try to figure out what sort of 'attention to safety' is most helpful. |
Chemistry World August 10, 2007 Richard Van Noorden |
Azadirachtin Sees First Total Synthesis A complex natural product has finally succumbed to its first total synthesis after 22 years of attempts by eminent organic chemists. |
Chemistry World August 29, 2006 |
Conference Blog About 3000 chemists have gathered in Budapest, Hungary, for the first European Chemistry Congress: Radish Sango on the Menu... Robots in the Lab... Speed Chemistry... etc. |
Chemistry World July 10, 2013 Karl Collins |
An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World May 29, 2013 Paul Docherty |
Pactamycin A member of a 'rival' field stating that a molecule is 'inaccessible by synthetic organic chemistry' is like a red rag to the proverbial bull. This challenge surrounds analogs of pactamycin, a complex cyclopentane-based target with an exceptionally potent biological profile. |
Chemistry World March 20, 2007 Tom Westgate |
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. |
Chemistry World November 2007 |
Book Reviews A review of books on: good clinical & laboratory practices, green chemistry, environmental chemistry, organic reactions in water, universal asymmetry, and molecular models for fluids. |
Chemistry World March 30, 2015 Katrina Kramer |
Chemistry: a very short introduction I heartily recommend this book -- it is an enjoyable read both for chemists and non-chemists alike. Part of the Very short introduction series, it fits perfectly into every suit or lab coat pocket. |
Chemistry World July 23, 2012 Melissae Fellet |
RNA wrapper protects small molecules Step aside benzene rings, there's a new protecting group in town. Dutch researchers have used a strand of RNA to cover portions of a complex small molecule. They then chemically modified a portion of the molecule not covered by the RNA. |
Information Today November 19, 2015 |
Thieme Updates Science of Synthesis Thieme Chemistry rolled out Science of Synthesis version 4.2, which has about 2,400 printed pages of new content. |
Chemistry World July 22, 2015 James Morey |
Organic synthesis: state of the art -- 2011--2013 This book would be ideal for those needing to be on top of the literature in synthetic organic chemistry, but who don't have the time to read the ever-increasing body of pertinent articles. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World July 14, 2011 Simon Hadlington |
Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor. |
Chemistry World December 20, 2007 Richard Van Noorden |
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World June 26, 2014 Rebecca Trager |
UCLA chemist avoids prison time for lethal lab accident Russ Phifer, executive director of the National Registry of Certified Chemists thinks the charges brought against Patrick Harran and UCLA have improved lab safety. |
Reactive Reports Issue 45 |
Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question... |
HHMI Bulletin Nov 2011 Robert Tjian |
President's Letter: Intellectual Ferment There are exciting connections between chemistry and biology from both "sides" of the disciplinary divide. |
Chemistry World July 2008 Dylan Stiles |
Column: Bench Monkey Work in a chemistry lab long enough, and I can just about guarantee sooner or later you'll battle an accidental fire. |
Chemistry World May 2007 Dylan Stiles |
Bench Monkey One has to wonder if Pauling, Sacks and Woodward would have ended up like they did if it were not for the very early hands-on experience they got with chemistry. Today's chemistry sets may be safer, but they're also a lot more boring. |
Chemistry World March 10, 2006 |
Dual Organometallics Enhance Zinc Reactivity Chemists have synthesised organometallic compounds that enable zinc to participate in directed metalation of organic substrates. |
Chemistry World October 12, 2015 Emma Stoye |
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84. |
Chemistry World May 2008 Dylan Stiles |
Bench Monkey It takes at least five years before an average chemistry student can form a hypothesis and test it in a laboratory. Even the most gifted stars of the field don't emerge until their mid-twenties. |