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Managed Care June 2004 Thomas Morrow |
Laronidase Opens Door To Treat Other Rare Disorders The release of alpha-L-iduronidase also demonstrates the wave of future treatments for many other mucopolysaccharidosis (MPS) diseases. |
American Family Physician June 15, 2005 Hall & Zalman |
Evaluation and Management of Apparent Life-Threatening Events in Children Many physicians have received a frantic call from an anxious parent stating that his or her child stopped breathing, became limp, or turned blue, but then quickly recovered. Approximately 50% of these children are diagnosed with an underlying condition that explains the apparent life-threatening event. |
American Family Physician October 15, 2001 Joseph J. Irwin |
Anemia in Children Anemia in children is commonly encountered by the family physician. Multiple causes exist, but with a thorough history, a physical examination and limited laboratory evaluation a specific diagnosis can usually be established... |
Nurse Practitioner September 2011 Cheryl L. Gainer |
Celiac Disease: Helping Patients Live Gluten-Free A review of the screening, diagnosis, and treatment of celiac disease. |
American Family Physician November 1, 2002 Hashim & Guillet |
Common Issues in the Care of Sick Neonates Some newborn infants require observation and care that is beyond the scope of a normal newborn nursery. In many hospitals, this level of care is designated intermediate, level II, or special care nursery. Infants in these nurseries may be managed by family physicians... |
American Family Physician November 15, 2003 Cooper et al. |
Primary Immunodeficiencies Primary immunodeficiencies include a variety of disorders that render patients more susceptible to infections. If left untreated, these infections may be fatal. The disorders constitute a spectrum of more than 80 innate defects in the body's immune system. |
American Family Physician March 1, 2002 John M. Sauret |
Rhabdomyolysis Rhabdomyolysis is a potentially life-threatening syndrome resulting from the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. The most common causes are crush injury, overexertion, alcohol abuse and certain medicines and toxic substances... |
American Family Physician October 1, 2005 Jennifer E. Frank |
Diagnosis and Management of G6PD Deficiency Glucose-6-phosphate dehydrogenase deficiency, the most common enzyme deficiency worldwide, causes a spectrum of disease including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis. Persons with this condition also may be asymptomatic. |
American Family Physician January 1, 2002 Mamta Fuloria & Shelley Kreiter |
The Newborn Examination: Part I. Emergencies and Common Abnormalities Involving the Skin, Head, Neck, Chest, and Respiratory and Cardiovascular Systems A careful examination at delivery helps the physician detect anomalies, birth injuries, and cardiorespiratory disorders that may compromise a newborn's successful adaptation to extrauterine life... |
American Family Physician August 1, 2005 Wattendorf & Hadley |
Family History: The Three-Generation Pedigree The three-generation pedigree provides a pictorial representation of diseases within a family and is the most efficient way to assess hereditary influences on disease. |
American Family Physician June 15, 2006 Prater & Zylstra |
Medical Care of Adults with Mental Retardation Primary medical care of persons with mental retardation should involve continuity of care, maintenance of comprehensive treatment documentation, routine periodic health screening, and an understanding of the unique medical and behavioral disorders common to this population. |
Nurse Practitioner October 2010 Dawn Lee Garzon et al. |
Providing Optimal Care for Children with Developmental Disorders Given the prevalence of children with developmental disorders, primary care providers need to educate themselves on how to diagnose and monitor this population. |
Managed Care June 2006 Thomas Morrow |
Pompe Disease Therapy Presents Coverage Challenge Although Myozyme is approved for the infantile form of Pompe disease, it is logical to extend coverage to patients with the late onset form. |
Nursing September 2010 Margaret M. Bolton |
Sounding the alarm about metabolic syndrome Any health problem that affects a third of American adults is sure to impact your nursing practice. Metabolic syndrome, a growing and commonly silent condition, poses a significant public health crisis. |
American Family Physician November 1, 2002 Prater & Zylstra |
Autism: A Medical Primer Autistic disorder, a pervasive developmental disorder resulting in social, language, or sensorimotor deficits, occurs in approximately seven of 10,000 persons. Early detection and intervention significantly improve outcome. |
American Family Physician October 1, 2000 Douglas L. Smith |
Anemia in the Elderly Anemia should not be accepted as an inevitable consequence of aging. A cause is found in approximately 80 percent of elderly patients. The most common causes of anemia in the elderly are chronic disease and iron deficiency... |
American Family Physician January 15, 2003 Pritts & Susman |
Diagnosis of Eating Disorders in Primary Care Eating disorders are associated with devastating medical and psychologic consequences, including death, osteoporosis, growth delay, and developmental delay. Prompt diagnosis is linked to better outcomes. |
Nurse Practitioner November 2009 Sandra M. Nettina |
A New Look at Vitamin B12 Deficiency Many patients, especially the elderly, have risk factors for vitamin deficiency. A wellness visit is the ideal time to include vitamin B 12 education, especially for those with risk factors for developing deficiency. |
American Family Physician March 1, 2003 Oh & Brown |
Vitamin B 12 Deficiency Vitamin B12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders. The role of B12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored. |
American Family Physician March 1, 2007 Killip et al. |
Iron Deficiency Anemia Iron deficiency anemia (IDA) is the most common nutritional deficiency worldwide. The U.S. Preventive Services Task Force currently recommends screening for iron deficiency anemia in pregnant women but not in other groups. |
American Family Physician June 15, 2004 Darwin Deen |
Metabolic Syndrome: Time for Action Family physicians can be more effective in helping patients to change their lifestyle behaviors by assessing each patient for the presence of specific risk factors, clearly communicating these risk factors to patients, identifying appropriate interventions to address specific risks, and assisting patients in identifying barriers to behavior change. |
American Family Physician October 1, 2002 Louis A. Kazal |
Prevention of Iron Deficiency in Infants and Toddlers The prevalence of nutritional iron deficiency anemia in infants and toddlers has declined dramatically since 1960. However, satisfaction with this achievement must be tempered because the prevalence of iron deficiency anemia in one- to three-year-old children seems to be increasing. |
American Family Physician November 15, 2000 Son & Kirchner |
Depression in Children and Adolescents Depression among children and adolescents is common but frequently unrecognized. It affects 2 percent of prepubertal children and 5 to 8 percent of adolescents... |
American Family Physician September 15, 2001 David S. Smith |
Health Care Management of Adults with Down Syndrome The family physician's holistic approach to patients forms the basis of good health care for adults with Down syndrome... |
Managed Care February 2005 Mark Zitter |
Managing Drugs for Rare Genetic Diseases: Trends and Insights Evaluates recent trends and challenges in health system management of exceedingly rare genetic diseases, from the perspective of the manufacturer, managed care organization, physician, and actuary. |
American Family Physician March 1, 2006 Robert C. Langan |
Discharge Procedures for Healthy Newborns Physicians should use a checklist to facilitate discussions with new parents before discharging their healthy newborn from the hospital. The checklist should include information on breastfeeding, warning signs of illness, and ways to keep the child healthy and safe. |
Pharmaceutical Executive September 1, 2008 Jeffrey S. Aronin |
The Orphan Opportunity The Orphan Drug Act was passed 25 years ago. But the challenge of actually getting rare disease drugs and therapies to patients still remains |
IndustryWeek February 1, 2003 Tonya Vinas |
Make Good Deeds Part Of Business Strategy IndustryWeek spoke with Sigma-Tau Pharmaceuticals COO Ken Mehrling about how his company has been able to produce orphan drugs, remain profitable and capitalize on technologies it has developed. |
Managed Care November 2006 Thomas Morrow |
Transgenic Drug Production Heads Back to the Farm The use of transgenic goats to produce a recombinant form of human antithrombin is much more efficient than using mammalian cell cultures. |
American Family Physician October 15, 2004 Randy K. Ward |
Assessment and Management of Personality Disorders Patients with personality disorders are common in primary care settings; caring for them can be difficult. The characteristics of these patients' personalities tend to elicit strong feelings in physicians, lead to the development of problematic physician-patient relationships, and complicate the task of diagnosing and managing medical and psychiatric disorders. |
American Family Physician August 1, 2000 |
Putting Prevention into Practice Screening for Iron Deficiency Anemia Among Children and Adolescents |
American Family Physician March 15, 2006 Shearer & Gordon |
The Patient with Excessive Worry Worry is an effective short-term response to uncertainty that can become self-perpetuating with adverse long-term consequences. Evidence-based treatments for such disorders can assist family physicians in the management of this disorder. |
Chemistry World April 2, 2015 Emma Stoye |
Horizon to acquire orphan drugs in $1.1bn Hyperion takeover Horizon will gain two rare disease drugs: Ravicti (glycerol phenylbutyrate) and Buphenyl (sodium phenylbutyrate), which are used to treat urea cycle disorder. |
Wired October 2006 Thomas Goetz |
The Thin Pill 75 million Americans may have something called metabolic syndrome. How Big Pharma turned obesity into a disease - then invented the drugs to cure it. |
AskMen.com Jen Woodward |
Minerals 101 You don't have to consult the periodic table to make sure your body is getting the minerals it needs. |
American Family Physician December 1, 2001 John Koo |
Psychodermatology: The Mind and Skin Connection Psychodermatology, or psychocutaneous medicine, focuses on the boundary between psychiatry and dermatology. Understanding the psychosocial and occupational context of skin diseases is critical to the optimal management of psychodermatologic disorders... |
Chemistry World November 5, 2012 Andrew Turley |
Approval for first gene therapy drug Alipogene tiparvovec, marketed as Glybera, has become the first gene therapy drug to win approval in either the US or the EU. |
Scientific American February 28, 2005 Gunjan Sinha |
The Diet That Fits With the understanding that some diseases such as obesity are metabolic syndromes in which multiple biochemical pathways interact to cause complex symptoms, metabolic testing offers a way to gauge health over a lifetime. |
AskMen.com Vatche Bartekian |
Are Vitamins Really Necessary? Because on average only 9% of all North American men consume the daily amounts vegetables and fruit recommended by the government, supplements are often used to help bridge the gap. Here are some facts about vitamins and minerals. |
The Motley Fool March 3, 2011 Ryan McBride |
With Sanofi Buyout of Genzyme, Rare Disease Execs Upbeat About Interest in Their Niche The field might benefit from the increased interest in it among pharmaceutical players. |
Chemistry World October 10, 2014 Rebecca Trager |
US ramps up rare diseases research The US National Institutes of Health is spending $29 million to fund research consortia that will study more than 200 rare diseases. |
BusinessWeek October 10, 2005 Catherine Arnst |
Is This Disease For Real? Metabolic syndrome may put you at higher risk for heart disease and diabetes, but many doctors question the diagnosis. |