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American Family Physician September 1, 2005 Wattendorf & Muenke	Prader-Willi Syndrome A review on Prader-Willi Syndrome (PWS) to aid physicians in recognizing and diagnosing children with this genetic disorder. PWS is the most common form of obesity caused by a genetic syndrome.
American Family Physician December 1, 2005 Wattendorf & Muenke	Klinefelter Syndrome This disease is caused by an additional X chromosome in males. Clinical findings are nonspecific during childhood; thus, the diagnosis commonly is made during adolescence or adulthood in males who have small testes with hypergonadotropic hypogonadism and gynecomastia.
Managed Care June 2004 Thomas Morrow	Laronidase Opens Door To Treat Other Rare Disorders The release of alpha-L-iduronidase also demonstrates the wave of future treatments for many other mucopolysaccharidosis (MPS) diseases.
Financial Advisor November 2006 Karen DeMasters	Special Needs, Special Advisor This former small-town mayor and now independent financial planner and president of a successful fee-based money management firm takes time out for folks with special needs.
American Family Physician November 1, 2002 Prater & Zylstra	Autism: A Medical Primer Autistic disorder, a pervasive developmental disorder resulting in social, language, or sensorimotor deficits, occurs in approximately seven of 10,000 persons. Early detection and intervention significantly improve outcome.
American Family Physician October 15, 2002 S. Sutton Hamilton	Evaluation of Clumsiness in Children Parents and physicians often dismiss seemingly minor motor difficulties in children. But approximately 6 percent of school-aged children have coordination problems serious enough to interfere with academic performance and social integration.
American Family Physician August 15, 2000 David S. Newberger	Down Syndrome: Prenatal Risk Assessment and Diagnosis
American Family Physician June 15, 2006 Prater & Zylstra	Medical Care of Adults with Mental Retardation Primary medical care of persons with mental retardation should involve continuity of care, maintenance of comprehensive treatment documentation, routine periodic health screening, and an understanding of the unique medical and behavioral disorders common to this population.
American Family Physician August 1, 2005 Wattendorf & Hadley	Family History: The Three-Generation Pedigree The three-generation pedigree provides a pictorial representation of diseases within a family and is the most efficient way to assess hereditary influences on disease.
American Family Physician September 15, 2001 David S. Smith	Health Care Management of Adults with Down Syndrome The family physician's holistic approach to patients forms the basis of good health care for adults with Down syndrome...
HHMI Bulletin May 2011 Madeline Drexler	Mark Bear: Charting New Waters Bear has applied his discoveries in brain plasticity to understanding fragile X syndrome, an inherited form of mental impairment.
American Family Physician August 1, 2003 Meyer et al.	Sudden Arrhythmia Death Syndrome: Importance of the Long QT Syndrome In approximately 5 percent of sudden cardiac deaths, no demonstrable anatomic abnormality is found. Some cases are caused by sudden arrhythmia death syndrome. A prolonged QT interval is a common thread among the various entities associated with sudden arrhythmia death syndrome.
Chemistry World September 13, 2012 Ian Le Guillou	Hope for autism treatments Two reports in Science over the past week point the way to potential treatments for some forms of autism.
American Family Physician August 15, 2000	Down Syndrome: What You Need to Know When You're Pregnant
Nurse Practitioner October 2010 Dawn Lee Garzon et al.	Providing Optimal Care for Children with Developmental Disorders Given the prevalence of children with developmental disorders, primary care providers need to educate themselves on how to diagnose and monitor this population.
American Family Physician April 15, 2006 Master-Hunter & Heiman	Amenorrhea: Evaluation and Treatment A thorough history and physical examination as well as laboratory testing can help narrow the differential diagnosis of amenorrhea. In patients with primary amenorrhea, the presence or absence of sexual development should direct the evaluation.
American Family Physician September 1, 2000	Polycystic Ovary Syndrome: It's Not Just Infertility Recent diagnostic and pharmacologic developments have focused renewed attention on polycystic ovary syndrome...
Nurse Practitioner June 2010 Laura M. Struble	Tremors: Learning to stop the shakes Identifying the type of tremor is necessary to determine underlying neurologic disorders. The gold standard for diagnosing tremors is still history and physical exam.
IEEE Spectrum November 2007 Josh Romero	Three-Dimensional Medical Imaging Could Improve Doctors' Ability to Diagnose Fetal Alcohol Syndrome Laser scanners could help diagnose a birth defect that's difficult to detect.
HHMI Bulletin Nov 2010 Sarah C.P. Williams	Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word
American Family Physician February 15, 2002 Miriam Grushka	Burning Mouth Syndrome Burning mouth syndrome is characterized by a burning sensation in the tongue or other oral sites, usually in the absence of clinical and laboratory findings...
American Family Physician February 15, 2002 Grace Brooke Huffman	Evaluating and Treating Unintentional Weight Loss in the Elderly Unintentional weight loss in the elderly patient can be difficult to evaluate. Accurate evaluation is essential, however, because this problem is associated with increased morbidity and mortality...
Managed Care November 2006 Maureen Glabman	Genetic Testing: Major Opportunity, Major Problems Whether a person is likely to develop diabetes, cancer, schizophrenia, or stroke will be reasonably well predicted, and tests can also determine whether a patient will respond to a given therapy. That's the good part.
American Family Physician October 15, 2003 Sharon Smaga	Tremor Tremor, a rhythmic, involuntary, oscillatory movement of body parts, is the most common movement disorder.
American Family Physician April 15, 2003 Adan & Crown	Diagnosis and Treatment of Sick Sinus Syndrome Sick sinus syndrome comprises a variety of conditions involving sinus node dysfunction and commonly affects elderly persons. While the syndrome can have many causes, it usually is idiopathic.
Chemistry World February 25, 2015 Rebecca Trager	US opens up home DNA screening The US Food and Drug Administration has, for the first time, authorized a genetic test to be sold directly to consumers. The agency plans to ease the regulatory path for similar screening tests.
American Journal of Nursing September 2009 Lockwood-Rayermann et al.	Original Research: Women's Awareness of Ovarian Cancer Risks and Symptoms Objective: To assess how well informed women ages 40 and older are of ovarian cancer symptoms and risk factors.
Wired October 2006 Thomas Goetz	The Thin Pill 75 million Americans may have something called metabolic syndrome. How Big Pharma turned obesity into a disease - then invented the drugs to cure it.
American Family Physician June 15, 2004 Darwin Deen	Metabolic Syndrome: Time for Action Family physicians can be more effective in helping patients to change their lifestyle behaviors by assessing each patient for the presence of specific risk factors, clearly communicating these risk factors to patients, identifying appropriate interventions to address specific risks, and assisting patients in identifying barriers to behavior change.
ifeminists June 10, 2003 Barbara Curtis	A Little Extra My son Jonathan has a little extra. A little extra enthusiasm, a little extra innocence, a little extra charm. Oh, and did I mention an extra chromosome? The one on the 21st pair that inspires so much fear in parents-to-be. Down syndrome.
American Family Physician November 15, 2006 Wolff & Wilson	Putting Prevention into Practice Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility.
American Family Physician September 15, 2001	Health Issues for Adults with Down Syndrome Are regular check-ups a good idea?... How can I help my relative with Down syndrome have a full life?... My older relative is having some new problems. Could it be Alzheimer's disease?...
Nursing September 2010 Margaret M. Bolton	Sounding the alarm about metabolic syndrome Any health problem that affects a third of American adults is sure to impact your nursing practice. Metabolic syndrome, a growing and commonly silent condition, poses a significant public health crisis.
BusinessWeek October 10, 2005 Catherine Arnst	Is This Disease For Real? Metabolic syndrome may put you at higher risk for heart disease and diabetes, but many doctors question the diagnosis.